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Description
S-RMab® MUC2 Recombinant Rabbit mAb,PBS Only (SDT-345-148)Product Specification Host Rabbit Antigen MUC2 Synonyms MRP, Mucin 2, MUC 2, Intestinal mucin 2, SMUC Immunogen Synthetic Peptide Location Cytoplasm, Secreted Accession Q02817 Clone Number SDT 345 148 Antibody Type Recombinant mAb Isotype IgG Application IHC P, IF Reactivity Hu Purification Protein A Concentration 1mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | MUC2 |
| Synonyms | MRP, Mucin-2, MUC-2, Intestinal mucin-2, SMUC |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Secreted |
| Accession | Q02817 |
| Clone Number | SDT-345-148 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P, IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:200 | |
| IF | 1:200 |
Background
Mucin 2, oligomeric mucus gel-forming, also known as MUC2. It is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80% by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium [PMID: 9722984].
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