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Ships within 48 hours · Estimated delivery Aug 11 - Aug 16
For Your Every Summer RSVP, with Code: SUMMER15
Description
IFN-alpha2 Recombinant Rabbit mAb (SDT-160-241)Product Specification Host Rabbit Antigen IFN alpha2 Immunogen Recombinant Protein Accession P01563 Clone Number SDT 160 241 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity Hu Cross Reactivity No cross reactivity against IFN alpha 1b, IFN Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer 50 mM Na citrate, pH 6. 0, 0. 9 % NaCl, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | IFN-alpha2 |
| Immunogen | Recombinant Protein |
| Accession | P01563 |
| Clone Number | SDT-160-241 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross-reactivity against IFN-alpha 1b, IFN-γ |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer |
50 mM Na-citrate, pH 6.0, 0.9 % NaCl, 0.03% Proclin 300
|
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
IFN-α is a cytokine that has an immunomodulatory function. It plays an important role not only in antiviral activity but also in several physiologic functions, such as activation of dendritic cells and accelerated expression of major histocompatibility complex I and II molecules that may cause increased antigen presentation. Variants of human leukocyte interferon α 2 (IFN-α 2a, α 2b, and α 2c) differ from each other by changes in their coding regions at nucleotide positions 137 and 170. IFN-α 2a is an important cytokine and used for antiviral and anticancer treatment.
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Exchange/Return Notes
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