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Description
PKC delta Recombinant Rabbit mAb (S-2611-39)Product Specification Host Rabbit Antigen PKC delta Synonyms Protein kinase C delta type; Tyrosine protein kinase PRKCD; nPKC delta; Pkcd; Prkcd Immunogen Recombinant Protein Location Cell membrane, Cytoplasm, Nucleus, Mitochondrion Accession P28867 Clone Number S 2611 39 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Mk Positive Sample 293T, HeLa, K562, A431, NIH 3T3, mouse brain, COS 7 Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | PKC delta |
| Synonyms | Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-delta; Pkcd; Prkcd |
| Immunogen | Recombinant Protein |
| Location | Cell membrane, Cytoplasm, Nucleus, Mitochondrion |
| Accession | P28867 |
| Clone Number | S-2611-39 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Mk |
| Positive Sample | 293T, HeLa, K562, A431, NIH/3T3, mouse brain, COS-7 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Mk |
| IHC-P | 1:200-1:1000 | Hu, Ms |
| ICC | 1:100 | Hu |
Background
Protein kinase C delta (PKCδ) is a serine/threonine kinase of the novel PKC subfamily that, once activated by diacylglycerol or oxidative stress, translocates to distinct subcellular compartments where it phosphorylates substrates such as caspase-3, p53, and STAT1 to regulate apoptosis, DNA-damage responses, immune signaling, and tumor suppression, and its catalytic activity is fine-tuned by tyrosine phosphorylation (e.g., Y311) and by the formation of complexes with receptors, adaptors, and lipids, making PKCδ a central but context-dependent switch between survival and cell death.
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