SKU: 85306299017

5-AT

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Description

5-ATIngredients in this product are not WADA approved. Do not take if you are tested by WADA standards. split 5 Etioallocholen 3b,7b,17b triol: More commonly known as androstenetriol, 5 etioallocholen 3 beta 7 beta 17beta triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions

Ingredients in this product are not WADA approved. Do not take if you are tested by WADA standards.

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5-Etioallocholen-3b,7b,17b-triol: More commonly known as androstenetriol, 5-etioallocholen-3 beta-7 beta-17beta-triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!

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Though DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).

Like DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.

In less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:

  • Preventing our muscle cells from uptaking glucose (inducing insulin resistance).
  • Preventing muscle protein synthesis.
  • The breakdown of glycogen (the compound responsible for that “full look”).
  • Suppressing the immune processes involved in muscle growth.

While these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.

Enter DHEA and its metabolite, androstenetriol. In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. In fact, androstenetriol is one of the most potent anti-glucocorticoids the body produces – exerting almost unbelievable effects in certain pro-inflammatory cell lines.

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SKU: 85306299017

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Kimberly Nelson
Omaha, US
★★★★★ 5
Best toy for a puppy who loves tug-o-war
My puppy (lab/shepherd) went nuts for this toy. She loves to play tug-o-war. This is so durable and the grip handles on the end totally help you out. She loves to bit in the middle and will whip it at you to get you to engage with her. The size is perfect for her and the KONG material must feel good for her.
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Reviewed in the United States on May 19, 2026
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GoldGirlGMA
Houston, US
★★★★★ 5
GREAT DOG TOY INDESTRUCTIBLE!
Best dog toy yet! My large breed year old pup is very hard on toys and this one stands up to the wild playing and chewing! Excellent purchase I’ll definitely buy it again to have extras around and I’d definitely give it as a gift! Happy dog happy life! GREAT PRODUCT
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Reviewed in the United States on January 23, 2026
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Heather Brubaker
Omaha, US
★★★★★ 1
Kong didn't survive this guy.
He had it for an hour.. We played tug for around 10 minutes then he took it off and chewed it up.. I thought Kongs were tougher to chew up.. very dissapointed.
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Reviewed in the United States on May 25, 2026
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Ginger Peck
Boise, US
★★★★★ 5
One of the best dog toys we've found
This is one of my little girl's favorite toys. She's an aggressive chewer so at first we followed the manufacturers instructions not to let her use as a chew toy. It was purchased in January 2025, but it's holding up just fine. She likes to turn it into a pretzel for some reason, but hey it keeps her entertained! Highly recommend.
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Reviewed in the United States on May 3, 2026
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Kevin Rubel
Alexandria, US
★★★★★ 4
Good for play but don’t leave out to be chewed on
With two labs we need durable toys. This can stand up to the teeth when pulling but we can’t leave it laying around or it has chunks chewed out of it. And it’s not the toys fault that my girls can’t figure out how to each take a side, so it’s a human vs dog pull toy.
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Reviewed in the United States on September 27, 2025

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