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Description
Keratin 14 Recombinant Rabbit mAb(SDT-023-1)Product Specification Host Rabbit Antigen Keratin 14 Synonyms Cytokeratin 14,CK 14, KRT14 Immunogen Synthetic Peptide Accession P02533 Clone Number SDT 023 1 Antibody Type Rabbit mAb Application WB, IHC P, ICC, IP Reactivity Hu, Ms Predicted Reactivity Rt Purification Protein A Research Area Signal Transduction Concentration 0. 5mg ml Molecular Weight 51kDa Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0.
Product Specification
| Host | Rabbit |
| Antigen | Keratin 14 |
| Synonyms | Cytokeratin-14,CK-14, KRT14 |
| Immunogen | Synthetic Peptide |
| Accession | P02533 |
| Clone Number | SDT-023-1 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC, IP |
| Reactivity | Hu, Ms |
| Predicted Reactivity | Rt |
| Purification | Protein A |
| Research Area | Signal Transduction |
| Concentration | 0.5mg/ml |
| Molecular Weight | 51kDa |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:1000 | |
| ICC | 1:500 | |
| WB | 1:1000 | |
| IP | 1:25 |
Background
Keratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14). In humans it is encoded by the KRT14 gene. Keratin 14 is expressed in mitotically active basal layer cells, along with its partner keratin 5 (K5), and their expression is down-regulated as cells differentiate. Keratin 14 has been studied as a prognostic marker in breast cancer. Keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and has been reported useful in the identification of squamous cell carcinomas.
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