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Description
CD72 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms CD72, LYB2, CD72b, Lyb2 Accession P21854 Amino Acid Sequence Arg117 Asp359, with C terminal human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | CD72, LYB2, CD72b, Lyb2 |
| Accession | P21854 |
| Amino Acid Sequence | Arg117-Asp359, with C-terminal human IgG1 Fc RYLQVSQQLQQTNRVLEVTNSSLRQQLRLKITQLGQSAEDLQGSRRELAQSQEALQVEQRAHQAAEGQLQACQADRQKTKETLQSEEQQRRALEQKLSNMENRLKPFFTCGSADTCCPSGWIMHQKSCFYISLTSKNWQESQKQCETLSSKLATFSEIYPQSHSYYFLNSLLPNGGSGNSYWTGLSSNKDWKLTDDTQRTRTYAQSSKCNKVHKTWSWWTLESESCRSSLPYICEMTAFRFPDIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 59-68kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Wu H J. et al. (2009) CD72, a coreceptor with both positive and negative effects on B lymphocyte development and function. J Clin Immunol. 29: 12-21. 2、Adachi T. et al. (1998) The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation. J Immunol. 160: 4662-4665. 3、Adachi T. et al. (2000) CD72 negatively regulates signaling through the antigen receptor of B cells. J Immunol. 164: 1223-1229. |
Background
CD72 is a coreceptor of B cell receptor (BCR), which is expressed on all B cells starting at the pre-B cell stage, but its expression decreases significantly during differentiation into plasma cells. CD72 is a transmembrane receptor that is expressed as a homodimer. It has a conserved intracellular domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that binds SHP-1, a tyrosine phosphatase, and an ITIM-like motif that binds Grb2, an adaptor protein required to activate the Ras pathway. CD72 is known to play an important role in various B cell processes, including proliferation, apoptosis and differentiation. Mouse CD72 negatively regulates BCR signaling by recruiting Src homology 2 domain-containing protein tyrosine phosphatase-1 (SHP-1) at ITIM.
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4.7 ★★★★★
Based on 27 reviews
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Product Reviews
★★★★★ 3
Busted spring on one side....
Color: Black, Size: 28-70"W x 48-120"H (Pack of 1), Color: Black, Size: 28-70"W x 48-120"H (Pack of 1)
I would have given it five stars except for the fact that 1) the instructions that come with it are miserable so you will definitely want to refer to the photos they have in the advertisement here, and 2) it appears that one of the vertical poles has a busted spring and I literally had to stuff some socks underneath it to make it hold. Definitely an eyesore, so I'm not thrilled about that.
With that being said, I'm in an apartment and I don't want to drill in the walls to hang a curtain rod. My sliding glass doors have a track that I was able to get brackets that fit over the track to hold a pole, but I had one window that I could not do that with. I thought this would be an interesting way to hang curtains without doing damage. I considered those sticky tape curtain rod holders, but I was reading a lot of bad reviews about them not holding or them taking the paint off upon removal. I figured this was the better option and it gave the room some nice aesthetics because my furniture is farmhouse white wood with black iron accents, so this blended really well with the aesthetics of the room. I know that most people who did reviews used this product as its advertised to be a room divider for privacy... So I figured this is a nice way to review using this product in a different way. I just really can't stand window blinds, as they look so commercial and industrial to me... I needed a way to make the space seem more homey.
While this is working fine for me, the reality is I have white lace curtains, which don't weigh much. I don't know that I could recommend this product, even though it says it can support a bit of weight, with curtains that are too heavy. Some of that, in part, is due to the fact that one of my springs is broken so it's not very stable as it is. However, even if I was not having the issue with the spring being busted on one side, I still don't think this would be good with heavy curtains (especially if you like opening your curtains frequently).
It did come with curtain hooks if you have the kind of curtains that allow you to use hooks to hang them. I do not. My curtains just slide onto the pole. If they were the type that could be put up with hooks then opening and closing them would probably be easier and maybe not as big of a deal as it is for me with the type of curtains I have.
I cannot comment on longevity as I just installed it today... If anything changes I will try to remember to come back and modify this review.
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Reviewed in the United States on July 6, 2025
★★★★★ 5
Easy setup works well
Color: Black, Size: 28-70"W x 48-120"H (Pack of 1)
I love these! Have bought two so far. Easy set up and no damage to walls. Room divider or window curtains. Works great!!
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Reviewed in the United States on January 6, 2026
★★★★★ 5
Easy to Put Together -
Color: Black
This was easy to put together. It is light weight. I use it in my spare room. And I have a light weight blanket I display, hanging over it.
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Reviewed in the United States on April 27, 2026
★★★★★ 5
Really great product
Color: Grey
It's really great it's just a bit wobbly.
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Reviewed in the United States on March 20, 2026
★★★★★ 3
Does not withstand any breeze.
Color: Grey
Not sturdy, tips over easily due to a small base and ultra light weight. Instructions were not much help but it’s pretty easy to figure out without them. Material is as expected.
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Reviewed in the United States on May 14, 2026