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Description
CD14 Mouse mAb (SDT-411-1)Product Specification Host Mouse Antigen CD14 Synonyms Myeloid cell specific leucine rich glycoprotein, Monocyte differentiation antigen CD14, FMC32lipopolysaccharide (LPS) Immunogen Synthetic Peptide Location Secreted, Golgi Apparatus, Cell membrane Accession P08571 Clone Number SDT 411 1 Antibody Type Mouse mAb Isotype IgG2a,k Application IHC P, IF Reactivity Hu Predicted Reactivity C. el Purification Protein G Concentration 1 mg ml Conjugation
Product Specification
| Host | Mouse |
| Antigen | CD14 |
| Synonyms | Myeloid cell-specific leucine-rich glycoprotein, Monocyte differentiation antigen CD14, FMC32lipopolysaccharide (LPS) |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Golgi Apparatus, Cell membrane |
| Accession | P08571 |
| Clone Number | SDT-411-1 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | IHC-P, IF |
| Reactivity | Hu |
| Predicted Reactivity | C.el |
| Purification | Protein G |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:1000 | |
| IF | 1:500 |
Background
CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. It helps to detect bacteria in the body by binding lipopolysaccharide (LPS), a pathogen-associated molecular pattern (PAMP). CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol (GPI) tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa).
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Exchange/Return Notes
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