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Description
LIN28 Recombinant Rabbit mAb (S-795-8)Product Specification Host Rabbit Synonyms Protein lin 28 homolog A, Lin 28A, Zinc finger CCHC domain containing protein 1, LIN28A, CSDD1, LIN28, ZCCHC1 Immunogen Synthetic Peptide Location Cytoplasm Accession Q9H9Z2 Clone Number S 795 8 Antibody Type Recombinant mAb Isotype IgG Application WB, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%
Product Specification
| Host | Rabbit |
| Synonyms | Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1, LIN28A, CSDD1, LIN28, ZCCHC1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | Q9H9Z2 |
| Clone Number | S-795-8 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IP | 1:50 |
Background
an RNA-binding protein that binds to and enhances the translation of the IGF-2 (insulin-like growth factor 2) mRNA. Lin28 binds to the let-7 pre-microRNA and blocks production of the mature let-7 microRNA in mouse embryonic stem cells. In pluripotent embryonal carcinoma cells, LIN28 is localized in the ribosomes, P-bodies and stress granules. LIN28 is highly expressed in human embryonic stem cells[14] and can enhance the efficiency of the formation of induced pluripotent stem (iPS) cells from human fibroblasts. LIN28 is a marker of undifferentiated human embryonic stem cells and has been used to enhance the efficiency of the formation of iPS cells from human fibroblasts.
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