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Description
ER alpha Recombinant Rabbit mAb (SDT-2950-36)Product Specification Host Rabbit Antigen ER alpha Synonyms Estrogen receptor; ER; ER alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1; ESR; NR3A1; ESR1 Immunogen Recombinant Protein Location Cytoplasm, Nucleus, Cell membrane Accession P03372 Clone Number SDT 2950 36 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu Positive Sample MCF7, T 47D Purification Protein A Concentration 0. 5 mg ml
Product Specification
| Host | Rabbit |
| Antigen | ER alpha |
| Synonyms | Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1; ESR; NR3A1; ESR1 |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm, Nucleus, Cell membrane |
| Accession | P03372 |
| Clone Number | SDT-2950-36 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Positive Sample | MCF7, T-47D |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500 | Hu |
| IHC-P | 1:250 | Hu |
| ICC | 1:500 | Hu |
Background
ER alpha (estrogen receptor alpha) is a 66-kDa ligand-activated transcription factor belonging to the nuclear receptor superfamily that, upon binding 17β-estradiol, translocates to the nucleus, homodimerizes, and recruits co-regulators to estrogen response elements (EREs) in target genes, thereby governing proliferation, differentiation, and survival in reproductive tissues, bone, cardiovascular system, and CNS, while its dysregulation drives breast and endometrial cancers, making it the principal therapeutic target of selective modulators (SERMs) and degraders (SERDs).
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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