SKU: 983081952

IL-21 Protein, Rat

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Description

IL-21 Protein, RatProduct Specification Species Rat Synonyms Interleukin 21, IL 21 Accession A3QPB9 Amino Acid Sequence His18 Ser146 Expression System E. coli Molecular Weight 15kDa Purity 95% by SDS PAGE&RP HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 400mM NaCl, pH8. 0 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.

Product Specification


Species Rat
Synonyms Interleukin-21, IL-21
Accession A3QPB9
Amino Acid Sequence His18-Ser146
Expression System E.coli
Molecular Weight 15kDa
Purity >95% by SDS-PAGE&RP-HPLC
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM Tris, 400mM NaCl, pH8.0
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.J Immunotoxicol. 2016 May;13(3):274-85.
2.Epub 2015 Oct 28. 2.Front Cell Infect Microbiol. 2019 Dec 4:9:401.
3.eCollection 2019. 3.Med Oncol. 2023 May 30;40(7):191.

Background

Cytokines are considered important factors in the modulation of various immune responses. Among them, interleukin (IL)-21 is one of the major immune modulators, adjusting various immune responses by affecting various immune cells. It has been suggested that IL-21 may enhance autoimmunity through different mechanisms, such as development and activation of helper T (TH)-17 and follicular helper T (TFH) cells, activation of natural killer (NK) cells, enhancing B-cell differentiation and antibody secretion and suppression of regulatory T (Treg) cells. Actually IL-21 is a pleiotropic cytokine whose functions in protection and immunopathology during parasitic diseases have been explored in limited ways, and it has been revealed to elicit antitumor-immune responses in several tumor models.

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SKU: 983081952

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4.7 ★★★★★
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Lars A. Morgan
Birmingham, US
★★★★★ 5
Fit my 2014 Odyssey TE
Size: 8.8" x 9.3" x 1.1"
Comes with printed instructions for those who haven't changed it before. Here is the specific use case from my van. On my 2014 TE its easy to access behind the glove box, open to usual full open then just push the left and right sides in to allow the glove box to come fully out. It may pop off of the mounts, don't panic it snaps right back on. Then look for the little rectangular panel with two small levers on either side. on the black plastic under the dash that you can now see and access. Press the levers and pull towards you, doing a bit of a wiggle to get it out. Its tight, but it will come out with having to break it. Don't gorilla hands it, it will break. There is a directional arrow on the filter, which you have to remove from the wrapper before installing. Yes, someone *will* forget that. Reassembly the reverse of removal. Check that video sharing site online if you need visual instructions.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 27, 2024
G
Verified Purchase
GreatDanes4U
New York, US
★★★★★ 5
K&N Filters are worth their cost in Filtration and Longevity!
Size: 8.3" x 8.4" x 0.6"
Tight fit, never needs replacement, only cleaning and reoiling. It has taken many miles to allow flow to resume after oiling for initial installation. Cold air intakes on numerous vehicles! I Love K&N filters for better filtartion and eventually cost savings!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 25, 2025
O
Verified Purchase
Oscar Miranda
Bozeman, US
★★★★★ 5
Excelente producto
Size: 8.3" x 8.4" x 0.6"
Excelente producto
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Reviewed in the United States on March 27, 2026
L
Verified Purchase
L&L Dangerfield
Bozeman, US
★★★★★ 5
Super Quality & Easy to install
Size: 8.3" x 8.4" x 0.6"
I've always loved K&N filters! This is no exception. As soon as you pull it out of the box, you feel the heavy duty quality and understand why these can last a lifetime. I highly recommend this and all K&N products. I replaced the in-cabin filter with this K&N filter as well as the engine filter on my 2004 4Runner Sport with the K&N option. I always place the sticker that comes in the box, right on or near the filter housing. Its a great reminder to clean and service the filter periodically. Don't waste any more like looking or researching, just buy this filter. You'll love it!
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Reviewed in the United States on July 7, 2020
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Verified Purchase
Ben
Grantham, US
★★★★★ 5
fits my Sienna 2006 with a little adjustment - sturdy, clean and happy that I brought it
Size: 8.3" x 8.4" x 0.6"
I brought this for my Camry 2006 and I have a Sienna 2004 as well that use the same regular cabin filter with the exact model. But when I put this K&N filter on my Sienna it doesn't fit well. The K&N filter sits in the plastic cabin filter frame exactly but there are four little plastic square on the side of the plastic frame sticking out that were in the way. I trim off the K&N border a bit and also the frame too in order to fit in. Beside a little adjustment, it works perfectly for my Sienna 2004. The smell is gone. I also use an oil pen to note on the K&N filter that "Do not replace" in case the dealer replace it during a maintain. I would buy more but this is life time I will buy another one for my camry. I am more than glad introducing this to my friends
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Reviewed in the United States on April 2, 2015

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