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MT-2

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Description

MT-2Research Use Only (RUO): Melanotan 2 (MT 2 MT II) is supplied strictly for invitro and laboratory research. Not for human or veterinary use, not for injection, not for consumption, and not for cosmetic application. What Is Melanotan 2 Peptide (MT 2 MT II MT2 Peptide)? Synthetic MSH Analog (RUO) Melanotan 2 (also abbreviated MT 2 or MT II) is a synthetic cyclic heptapeptide described as an analog of alpha melanocyte stimulating hormone (MSH). In

⚠ Research Use Only (RUO): Melanotan 2 (MT-2 / MT-II) is supplied strictly for in‑vitro and laboratory research. Not for human or veterinary use, not for injection, not for consumption, and not for cosmetic application.

What Is Melanotan 2 Peptide (MT-2 / MT-II / MT2 Peptide)? Synthetic α‑MSH Analog (RUO)

Melanotan 2 (also abbreviated MT-2 or MT-II) is a synthetic cyclic heptapeptide described as an analog of alpha-melanocyte-stimulating hormone (α‑MSH). In controlled research settings, the melanotan 2 peptide is used to explore melanocortin receptor signaling and pathway‑level readouts relevant to melanogenesis, CNS signaling, and metabolic research models. This page is provided for laboratory context only.

SEO note (natural terms used on-page): Researchers may also search for melanotan 2 peptide, MT2 peptide, MT-II peptide, alpha MSH analog peptide, and melanocortin receptor agonist. These phrases are integrated below in RUO-safe, non-clinical context.

 

Melanotan 2 (MT-II / MT2 Peptide) Specifications — CAS 121062-08-6, ≥99% HPLC Lyophilized Powder

Product Name Melanotan 2 (MT-II)
Sequence Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-NH2
CAS Number 121062-08-6
Molecular Formula C50H69N15O9
Molar Mass 1024.18 g/mol
Purity ≥99.0% (HPLC verified)
Form Lyophilized white powder
Verification HPLC / MS tested (batch-based)
Documentation CoA / SDS available upon request
Grade Research Use Only (RUO)

Melanotan 2 Mechanism: Melanocortin Receptor Agonist (MC1R, MC3R, MC4R, MC5R) — Research Context

Melanotan 2 is frequently referenced as a non‑selective melanocortin receptor agonist, with activity reported across MC1R, MC3R, MC4R, and MC5R in experimental systems. Its cyclic structure is commonly described as supporting enhanced stability compared with linear α‑MSH analogs, which is useful for reproducible assay design and receptor‑signaling workflows.

Where to Buy Melanotan 2 Peptide (MT-II / MT2) — Research-Grade Supplier with CoA, HPLC, MS

If you're searching where to buy melanotan 2, prioritize a supplier that labels MT‑2 strictly as Research Use Only and supports reproducibility with HPLC purity verification, MS identity confirmation, and batch traceability (CoA/SDS). Peptides Skin supplies melanotan 2 lyophilized powder for controlled research workflows and qualified laboratory buyers.

Melanotan 1 vs Melanotan 2: Difference Between Melanotan 1 and 2 in Research Models

A common query is what is the difference between melanotan 1 and 2. In research literature, MT‑1 and MT‑2 are discussed as α‑MSH‑related peptides that can differ in sequence design, receptor activity profiles, and experimental behavior. Researchers typically select MT‑2 vs MT‑1 based on study goals, receptor subtype focus (e.g., MC1R/MC4R), and assay endpoints.

Melanogenesis & Pigmentation Research: MC1R Signaling Pathways Studied with Melanotan 2

The melanotan 2 peptide is widely used to study melanogenesis in model systems, including MC1R‑linked signaling and downstream pathway markers associated with melanin production. These experiments may support broader investigations into photobiology, pigmentation biology, and cellular response pathways in non‑clinical models.

How to Store Melanotan 2 Peptide (MT2 / MT-II): Lyophilized Storage, Stability & Light Protection (SOP)

For how to store melanotan 2, laboratories typically keep lyophilized MT‑2 at −20°C, protected from light and moisture. Storage should follow your facility SOP and batch documentation. To minimize variability, avoid repeated temperature cycling and limit exposure to humidity.

How Long Does Melanotan 2 (MT2 Peptide) Last in the Fridge? Prepared-Solution Stability (RUO)

Another frequent question is how long does melanotan 2 last in the fridge. Stability depends on solvent system, concentration, container, and contamination controls. For RUO workflows, prepared solutions are usually treated as short‑term and refrigerated per SOP, with aliquoting used to reduce repeated freeze–thaw cycles. Always follow the stability window defined by your protocol and documentation.

How to Reconstitute Melanotan 2 (MT-II / MT2 Peptide) for Lab Assays — RUO, No Administration Guidance

Searches for how to reconstitute melanotan 2 are common. In research workflows, reconstitution is performed using sterile technique and an appropriate laboratory‑grade aqueous solvent selected for the assay. Solvent choice, pH, and final concentration are protocol‑dependent; follow your lab SOP and do not use this product for any human or veterinary purpose.

Why Choose Peptides Skin for Melanotan 2 (MT-II / MT2 Peptide) Research Supply

  • Verified purity: ≥99% HPLC verified (batch-based)
  • Documented identity: MS confirmation and CoA availability
  • Traceability: lot documentation for reproducible laboratory workflows
  • Secure logistics: packaging optimized to help protect stability in transit

Frequently Asked Questions (FAQs) — Melanotan 2 (MT-2 / MT-II) RUO

What is Melanotan 2 (MT-2 / MT-II / MT2 peptide)?

Melanotan 2 is a synthetic cyclic heptapeptide described as an α‑MSH analog used in laboratory research to investigate melanocortin receptor signaling and related pathway readouts in controlled models.

Where to buy Melanotan 2 for research use only?

When evaluating where to buy melanotan 2 for research, select an RUO‑labeled supplier that provides batch documentation (CoA/SDS) and analytical verification such as HPLC and MS.

What is the difference between Melanotan 1 and 2?

Melanotan 1 vs melanotan 2 differences are typically discussed in terms of sequence design and receptor activity profiles. Selection depends on the model, receptor target, and endpoints defined by the study.

How to store Melanotan 2 and how long does it last in the fridge?

Lyophilized MT‑2 is commonly stored at −20°C. Prepared solutions are typically refrigerated short‑term per SOP; stability depends on solvent and protocol, so follow your lab documentation.

How to reconstitute Melanotan 2 in lab workflows?

Reconstitution should be performed using sterile technique and an appropriate laboratory‑grade solvent selected for your assay. Do not interpret this as administration guidance.

WARNING — Research Use Only (RUO):
For laboratory research and development purposes only. Not for human or veterinary use, injection, consumption, or cosmetic application. Not intended to diagnose, treat, cure, or prevent any disease. Any mention of mechanisms refers exclusively to controlled research models.
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SKU: 39531703527

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4.2 ★★★★★
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Product Reviews
D
Darcy W.
Massapequa, US
★★★★★ 5
A beautifully crafted invitation to journal
Format: Paperback
Lilias Trotter Legacy’s latest book Beholdings is not so much a text as it is a beautifully crafted invitation. Inspired by the journals and sketches of Lilias Trotter (1853-1928—English missionary to Algeria, artist, writer, and journaler par excellence), biographer Miriam Rockness invites the reader to try their own hand at journaling, using Trotter as a model and guide. Rockness herself is no stranger to journaling, and her Preface to Beholdings enumerates the many benefits that await any reader who is willing to commit to the discipline for a period of time. In the short term, Rockness describes how journaling encourages one to focus, to pay attention, to take the time to behold the beauty in the world before one’s very eyes. Each page following the Preface includes a quote designed to stir the imagination, and an image from Trotter’s journals to illustrate what it means to behold an acorn, a flower petal, a sunrise in the Algerian desert. It is not just to see what is before one’s eyes, but to hold it in the mind’s eye and cherish it. As Simone Weil said, “Attention, taken to its highest degree, is the same thing as prayer. It presupposes faith and love.” It is this kind of attention that Rockness encourages the journaler to cultivate, and it is the kind of attention that Lilias Trotter so artfully illustrates. There is ample space on each page for the journaler, thus inspired, to record his or her observations, musings, sketches, or doodles. In the longer term, Rockness suggests that journaling helps cultivate a sense of proportion and perspective. She describes looking back with her husband over her journals from years before, reliving the moments that might otherwise have been forgotten, and allowing those glimpses in the rear view mirror to inform present day experience. Sometimes one finds that images seen in the rear view mirror really are smaller than they appeared at the time! In addition to being an incitement to journaling, Beholdings is a beautifully produced creation in its own right. Great thought has gone into the selection of the typeface, the texture and feel of the paper, the quality of the images reproduced. This makes Beholdings not only a delight to own, but also an exquisite gift to offer. My advice: buy one for yourself, and another for someone you love.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 16, 2022
W
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WellBCare
Louisville, US
★★★★★ 2
Be clear that it's a blank journal you create, with brief quotes and thumbnail art
Format: Paperback
If one is looking for a personal journal of empty lined pages ~ and a brief Lilias Trotter quote with a thumbnail-size photo of her art on each page then this is for you. I understood it was a book of her journalling with more viewable-size sketches.
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Reviewed in the United States on May 13, 2022
E
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Eric Balkan
San Leandro, US
★★★★★ 5
When and where economics went wrong
Format: Paperback
This is one of those books that can provide an epiphany to the reader -- but not very many American readers have even heard of it, unfortunately. That could be due to it's being a book primarily about English economic history, with assumptions that the reader is familiar to some extent with things like the Poor Laws and Tory socialism. But I wasn't, and was still able to glean some great insights from the work. That could be because Polanyi is not afraid of repetition. :-) A key insight, and the one that could be summed up as the theme of the book, is Polanyi's realization that prior to about 1830, the market and the economy were considered part of society. That is, economic activity was something that people did along with everything else they did, like engage in social/familial relationships, religious rituals, etc. But with the 1830s came a paradigm shift: the advent of rational capitalism. Now, the market was considered an entity by itself, outside of society. This market entity was viewed as governed by universal laws. Like laws of physics, these market laws were independent of culture, independent of social group, independent of time period, and, in fact, independent of human behavior. While any observer of human nature would say that people often make decisions for emotional reasons -- and modern neurological research shows that virtually every decision we make is a combination of the rational and the emotional -- these market laws assumed only rational behavior on the part of economic actors. Though Polanyi doesn't mention it, it's now easy to see how Alfred Marshall could get carried away with creating a mathematical foundation for microeconomics and how Leon Walras could, reportedly, say that if something couldn't be studied mathematically, it wasn't worth studying. There's no current way to model emotions with math, and so the Ricardian prototype of an emotion-less economics continues into the modern economics of today. These universal market laws frees the market from any social constraints. A number of modern neo-classical economists assert that this makes economics purely amoral, i.e., without regard for any ethics. Therefore any attempts by the public, by politicians, or by workers to add ethics to the market is an interference with pure market workings, which, according to their interpretation of Adam Smith's "invisible hand", will produce optimal results if just left alone. But Smith never said that, and in fact rational capitalism, in elevating greed and selfishness to the status of goals -- see the Ayn Rand work "The Virtue Of Selfishness" -- is, IMO, not amoral at all, but rather is a morality of its own. Anyway, back to Polanyi's insights. Another key one is the concept of a "double movement" in 19th century England. Each move to create a purer market created an ad-hoc counter move. E.g., Ricardian free trade was faced with opposition from workers losing their jobs and local firms losing business Americans can easily think of another example: where the employment of children (eventually) led to laws restricting that employment, simply because human beings have too much of a sympathetic nature to sit still for children losing limbs in the dangerous factories and mines of the time. Polanyi notes that capitalists often blame these anti-capitalist laws on planned activity by socialist anti-market groups, but he says they're actually the result of the recognition by the general public that they don't want to live under a pure market system. Yet another good insight is Polanyi's recognition that market laws treat labor, land, and money as commodities. We can see that today, where neo-classical economists assert that the law of supply and demand should apply to workers as it applies to anything else in the economy. That is, if there's a surplus of workers in one area and a shortage in another, supply and demand dictates the flow of workers from the one area to the other. But a laid-off textile worker in South Carolina is not going to move to China for a job. That's my own example, but Polanyi offers his own from modern English history. The book isn't perfect. Polanyi does have a tendency to generalize, a common failing among authors, IMO. E.g., in discussing the rise of fascism in the 1930s, he's on very shaky ground when he starts talking about the US or about Russian policy intentions during that period. I gave The Great Transformation 5 stars because, even with its faults, the reader will be thinking about Polanyi's insights for some time to come. I am.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 18, 2009
K
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Kindle Customer
Draper, US
★★★★★ 5
Not light reading but worth it
Format: Kindle
Much of this book was heavy reading for me, mainly due my not being familiar with the background development and history of various economic theory and associated laws over 500 or so years of British history. I did stick it out and am glad I did. There are many insights as to how we have arrived at today and the book is still relevant even though it was written in 1942. I found the last few chapters and the comments in Sources to offer the most explanations to fit modern times especially with regard to the rise of fascism. Thick but worth it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 6, 2025
B
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Blake West
Waukegan, US
★★★★★ 4
Interesting anthropology and critique, but dense and obtuse writing
Format: Kindle
The good part is that at the end of the day, I learned a lot here, and Polanyi raised a lot of very interesting and under-discussed historical points to create his argument. It felt very similar to David Graeber (or I guess Graeber is similar to Polanyi) in that way. The bad part is that, whereas Graeber writes with exceptional clarity and vividness, Polanyi is obtuse and dense. And I've read other books from this era, I don't think it's the time. I think it's Polanyi's writing. Beyond that, his work serves more as analysis than prescription. It's a bit unclear exactly what he's advocating for. Which maybe is OK, though I prefer when non fiction writers offer solutions rather than just pointing out problems. All in all, if you can settle in with his writing, there are definite gems in there.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 5, 2026

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