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Description
SR-9011 Solution, 600MG (20mg/mL)SR 9011 SR 9011 is a research drug developed by Professor Thomas Burris at the Scripps Research Institute. It acts as an agonist for Rev ErbA with a half maximal inhibitory concentration (IC50) of 790 nM for Rev Erb and an IC50 of 560 nM for Rev ErbA. This drug is primarily used in studies exploring the regulation of circadian rhythms and its potential implications for the immune system, inflammation, and cancer. SR 9011 belongs to the second
SR-9011
SR-9011 is a research drug developed by Professor Thomas Burris at the Scripps Research Institute. It acts as an agonist for Rev-ErbAα with a half-maximal inhibitory concentration (IC50) of 790 nM for Rev-Erbα and an IC50 of 560 nM for Rev-ErbAβ. This drug is primarily used in studies exploring the regulation of circadian rhythms and its potential implications for the immune system, inflammation, and cancer.
SR-9011 belongs to the second generation of Rev-ErbA activators and is found in high concentrations in various tissues such as the liver, skeletal muscles, adipose tissue, and the brain.
For more information, see the study on SR-9009 and SR-9011
Concentration
20mg/ml.
half-life
4 hours.
DISCLAIMER
This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary or domestic use. Please familiarize yourself with our DISCLAIMER before ordering.
Included is a precision pipette marked per 0.2 ml!
Shake well before use.
Data sheet
SR9011 – Solution, 600mg (20mg/mL)
| Application | Rev-ErbA Agonist |
| CAS | 1379686-29-9 |
| Molar Mass | 479.04 g/mol |
| Chemical Formula | C23H31ClN4O3S |
| IUPAC Name | 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide |
| Synonyms | SR9011, 1379686-29-9, SR-9011, CHEMBL1961797, GTPL8900, MolPort-044-561-120, PPUYOYQTTWJTIU-UHFFFAOYSA-N, KS-00000TT2, BDBM50366239, AKOS030526466, CS-4668, SR 9011, NCGC00347956-01, AK547296, HY-16988, 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-, 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide |
| Storage | Store at room temperature, tightly sealed, away from heat, light and moisture. |
| Solubility | Soluble in DMSO, Ethanol. Slow degradation in PEG400 |
| Organoleptic Profile | Clear liquid |
| Physical Form | Solution in PEG-400 , Ethanol |
| Specification | 20mg/mL ±5% |
| Terms | This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering. |
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