SKU: 12783444221

NMN Pro 250™ Sustained Release - Uthever® NMN, 250 mg, 60 tabs - Living Machine™ - 3-Pack

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Description

NMN Pro 250™ Sustained Release - Uthever® NMN, 250 mg, 60 tabs - Living Machine™ - 3-PackCombat Aging, Improve Heart Health and Promote Muscle Strength NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression. Nicotinamide mononucleotide (NMN) is a derivative of the B vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+. NMN Pro 250 Sustained Release is

Combat Aging, Improve Heart Health and Promote Muscle Strength

  • NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.
  • NMN Pro 250 Sustained Release is designed to slow and prolong NMN absorption, allowing a longer steady blood level concentration of the active ingredient. This enables NMN Pro 250 Sustained Release to be given at higher doses less frequently.

View Certificate of Analysis

Research Supported Benefits:

Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)

Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)

Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)

Supports Healthy Cognition. Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7)

Supports Healthy Skin. In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. (8,9)

References:

1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004

2. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287

3. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287

4. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080/08982104.2020.1820521

5. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016/j.jphotobiol.2021.112238

6. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755

7. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5

8. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442-

9. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013

10. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192

11. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016/j.brainres.2016.04.060

12. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016/j.cmet.2011.08.014

13. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985

Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 60
Amount Per Serving %DV
Uthever® β-Nicotinamide mononudeotide (NMN)
250 mg
† Daily Value not established
REV. 10.23
  • OTHER INGREDIENTS: Isomalt, modified pea protein, stearic acid, calcium palmitate, hydroxypropyl cellulose, pharmaceutical glaze.
  • SUGGESTED DAILY USE: Take 1 to 4 tablets in the morning, or as recommended by your healthcare practitioner.
  • NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken.
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product. KEEP OUT OF REACH OF CHILDREN 
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.
  • NMN Pro 250 Sustained Release is designed to significantly enhance NAD+ production and absorption by raising NMN and NAD+ blood levels for up to 6 hours compared to approximately 6 minutes for non-stabilized NMN in animal studies. The gel barrier around the tablet effectively protects the NMN from harsh gastrointestinal acids and upon reaching the intestines can be released slowly.
  • Only Clincially-Proven NMN. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.
  • Unique Delivery Method. NMN Pro 250 Sustained Release is designed to significantly enhance NAD+ production and absorption by raising NMN and NAD+ blood levels for up to 6 hours compared to approximately 6 minutes for non-stabilized NMN in animal studies. The gel barrier around the tablet effectively protects the NMN from harsh gastrointestinal acids and upon reaching the intestines can be released slowly.
  • Solvent-Free. Compared to other NMN products, ours is made without any chemical solvents.
  • Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
  • Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
Be Aware of Fake NMN: Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
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  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 12783444221

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4.5 ★★★★★
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Mr. Veritas
Battle Creek, US
★★★★★ 5
Sony STR-DH190 is an Amazing Deal. Don't pass it up.
Style: Stereo Receiver, Configuration: Receiver
I bought my STR-DH190 receiver to put in my "man cave" pool room. I respect SONY products, but I realized this 2-channel stereo receiver was a budget item, seemingly so inexpensive it must just be an entry-point-only receiver. I was shocked by its quality, sturdy construction, versatility and audiophile sound. It has Bluetooth connectivity, and a phono input for turntables. I hooked up a CD player, turntable, reel-to-reel, cassette deck, iPod, sub woofer and two sets of high end bookshelf speakers. The fronts are SONY Sscs5 3-Way 3-Driver Bookshelf Speakers. The rears are Polk. The sound is shocking, and everyone who hears it can't believe how it rocks. Now that this receiver is actually on sale at almost a "give-away" price, I'm tempted to buy another one as a backup in case one of my other systems needs a replacement receiver. It is Bluetooth ready, so I pair an Echo Dot with it for streaming. It is an amazingly versatile and reliable product. Highly Recommended.
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Reviewed in the United States on July 9, 2025
P
Verified Purchase
Phasedin
Grantham, US
★★★★★ 4
Quite Good, but maybe lacking a few inputs, Optical Audio and AM radio
Style: Stereo Receiver, Configuration: Receiver
Very basic, but seems to be the usual good quality Sony product. I bought this when my decades-old SOny receiver finally bit the dust. This receiver, at a decent price is a LOT more basic than my decades-old earlier receiver. That receiver had multiple inputs-many which I didn't use but were there for audiophiles all the same. Things like inputs for DAT, inputs for MD audio. analog videos in and out, Super video in and out, Component video, standard cassette deck, phono, component video (multiple), DVD in and out, component video, and more audio channel options I can't even remember. And as old as this receiver was it actually had Optical audio as well! I REALLY wanted to replace that old receiver with the exact same thing. albeit the modern model but that doesn't exist. SO I bought this one. Take a look and you'll see very few inputs, but oddly it had all the ones I actually needed for my old set-up-with NO extras though. I'm kind of shocked that this receiver doesn't even have the Optical audio which is kind of a standard now for modern TVs and I had to actually buy a cheap little 'converter box' which takes the optical cable and converts the digital audio into the standard RCA analog audio and I plug that into one of the available inputs in the receiver so that I can play my TV sound through the receiver/stereo system. I'm still kind of shocked that this receiver doesn't have that Optical, that would be the first thing i'd add to really make this a bargain and much more desirable. So I had to have a receiver for my old cassette deck, phono, etc. and standard CD player as well as DVD/Blu Ray audio sound (as concert DVDs don't sound too good on the standard speakers which come with modern TVs. So i've used EVRY input in this new unit and I really couldn't have bought it if it had a single less input. So in addition to having an input for Optical audio the other thing I wished it had was a receiver for AM radio, even if AM isn't too popular anymore. So maybe the lack of the Optical audio, additional inputs for other sources and no AM radio is the reason why this receiver is so reasonably priced, but well, i'm happy with it all the same.
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Reviewed in the United States on April 27, 2026
B
Verified Purchase
Blkjag
Port Orchard, US
★★★★★ 5
Great product
Style: Stereo Receiver, Configuration: Receiver
This is a great basic receiver. It's very easy to understand, setup and operate. This receiver sounds excellent and includes Bluetooth so I can stream Apple Music and Spotify to the receiver. My only negative comments would be that the speaker connections are the spring-loaded terminals which require thin gauge speaker wires or Flex Pin Banana Plugs. Also, you should be aware the FM Antenna (provided) is a wire antenna utilizing a strange plug-in adapter. It was perfectly adequate for what I needed however I think it could be an issue if you were in a remote area that required a mast antenna.
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Reviewed in the United States on April 9, 2026
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Verified Purchase
JLJ
Natrona Heights, US
★★★★★ 5
Shockingly Great: Do Not Be Skeptical Of The Ultra Low Price
Style: Stereo Receiver, Configuration: Receiver
Do not allow the extremely low price on this Sony STRDH 190 stereo receiver to in any way prejudice you against considering it as a wonderful entry-level stereo receiver. I have purchased thousands of products on Amazon over the past 25 years, and I cannot think of any item that pleasantly surprised me more profoundly than this one. I also purchased the matching (style) Sony turntable PS-LX310BT which works perfectly with the STRDH 190 receiver. Sony's lowest priced receiver now sells for the astounding bargain price of only around $200, though I caught it on sale for closer to $150... and as impossible as this is the believe, it has in recent years gone on sale for as little as $99(!) I have no idea how Sony makes a profit at these price levels. Now I know, most people would think, "there is just no way a $200 receiver is high quality"... but I am telling you, that is dead wrong in this case, and you should prepare to be blown away by what you get at this crazy low price point. This is NOT a no frills unit. It is feature packed. It has connections for TWO PAIR (four total) speakers, and PLENTY of clean no-distortion power to drive all four speakers to loud and clear volume levels. It also has an A/B speaker switch to play through speaker set A, or speaker set B, or all four speakers at once. It has a phono stage pre-amp which is actually very good. Seriously, it is much better than the phono stage pre-amp built into my Emotiva integrated amp for which I paid $1,000. It plays vinyl loud with no distortion. You will NOT need an external phono pre-amp. It has excellent Bluetooth wireless connectivity built in... no trouble getting it to instantly recognized sources and play them perfectly. You can play all the music on your iPhone or other digital device, wirelessly. It has a huge allotment of extra connections, ... a whopping FOUR inputs... so you can also hook up a CD player, and another external device of your choice, and another one after that, and another one after that! (WOW). And that's is not counting your PHONO input which is actually a fifth input connection. Astounding accommodation of external sources at this (or almost any) price point. If you are a dinosaur who listens to FM ... it's got an FM receiver with 30 station presets, and an output to hook up a proper external FM antenna, and a long-wire FM antenna is included in the package Sony says the "HiRes" audio produced by this unit is "superior to CD quality"... though I am not sure how to measure that claim, especially if the extrnal source you are using is a CD player. It comes with a very high quality remote control, with real buttons, and many features. You can actually program each of your external sources to appear in the illuminated display as the specific names you want, rather than a generic default source name like "CD". The low price may raise an eyebrow, and the fairly light weight (much heavier on one side than on the other curiously) nature of the unit may also cause doubt... but only until you set it up and start listening, and your jaw drops. I would put this sub-$200 receiver up against any receiver on the market priced under $800, (and probably several of them priced at twice that much!) and I believe you will not be disappointed in the sound quality of Sony's entry-level unit. You certainly will NEVER find another receiver anywhere near this price point with so many features and inputs... all of which work flawlessly. This is the greatest bargain in the world of affordably-priced HiFi equipment. It is easily worth multiple times the asking price.
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Reviewed in the United States on May 18, 2025
I
Verified Purchase
Ink Independent
Dallas, US
★★★★★ 5
Overall Excellent - Thorough Review - READ ME
Style: Stereo Receiver, Configuration: Receiver
I'm not an audiophile per se, but I do have elevated listening preferences. I enjoy finding the value in devices, and system configs. So that's the reason I tried this more budget-friendly receiver. Aesthetics: The look is very sleek and modern, which is great but sometimes I miss the nostalgia of more knobs. There is no base/treble knob and most everything is controlled by remote. That's fine I suppose, just be aware. The volume knob is very large and traditional which I love, but is also very stiff and not buttery smooth like you might expect. Perhaps that will break-in. Sound Quality: Wow, this sounds incredible. There is definitely a DSP happening that is noticeably awesome. It's referred to by Sony as Pure Direct. If you want to by-pass this, you can, but you'll hear right away the difference is major. I'm using simple Klipsch bookshelf speakers, and my expectations are surpassed on how much they come to life with bright and rich sound. Definitely a nice pairing for those shopping for speakers along with this unit. Overall the SQ is gonna be tough to beat without spending exponentially more. Remote: The remote is nice, sleek, and has what you need to quickly access. No complaints there. Installation: Takes minutes, super easy. Didn't follow any instructions due to my general confidence hooking up home audio gear. Overall: I highly recommend this one, and I'm picky. Initially, I fully expected to return this receiver, but plan to keep it. The only thing that may change my mind, is if I miss the nostalgia... then I'll have to go vintage. But no way a vintage receiver will sound this good. Props to Sony. Well done :) A+
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Reviewed in the United States on January 18, 2024

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