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Description
NO-SPA - 24 TabletsNo spa is indicated in such ailments as spasmodic conditions of smooth muscles associated with diseases of the biliary tract, spasmodic conditions of smooth muscles of the urinary tract. Supportively in spasmodic conditions of smooth muscle of the gastrointestinal tract. Action Synthetic drug with spasmolytic action. The diastolic effect of drotaverin does not depend on the type of innervation and location of smooth muscle (gastrointestinal tract,
No-spa is indicated in such ailments as - spasmodic conditions of smooth muscles associated with diseases of the biliary tract, spasmodic conditions of smooth muscles of the urinary tract. Supportively in spasmodic conditions of smooth muscle of the gastrointestinal tract.
Action
Synthetic drug with spasmolytic action. The diastolic effect of drotaverin does not depend on the type of innervation and location of smooth muscle (gastrointestinal tract, genitourinary tract, circulatory system and biliary tract). In the mechanism of action of drotaverin, the effect on phosphodiesterase plays a role, causing an increase in the concentration of cAMP and and a decrease in the concentration of calcium ions in the cell. After oral administration, the drug is well absorbed from the gastrointestinal tract. It is metabolized in the liver. It is excreted mainly in the urine and to a lesser extent in the bile.
Indications
Smooth muscle spasm conditions associated with biliary tract diseases: cholelithiasis, cholecystitis, cholecystitis, cholangitis, cholangitis, Vater's papillitis. Spasmodic conditions of the smooth muscles of the urinary tract: kidney stones, ureteral stones, inflammation of the renal pelvis, cystitis, painful urinary urgency. Supportively in spasmodic conditions of smooth muscles of the gastrointestinal tract: peptic ulcer disease of the stomach and duodenum, gastritis, enteritis, colitis, spasmodic conditions of the gullet and pylorus of the stomach, irritable bowel syndrome, spastic constipation and intestinal flatulence, pancreatitis; in spasmodic conditions of the reproductive tract: in painful menstruation, inflammation of the appendages, severe labor pains, threatened miscarriage; in headaches of vascular origin.
Action
Synthetic drug with spasmolytic action. The diastolic effect of drotaverin does not depend on the type of innervation and location of smooth muscle (gastrointestinal tract, genitourinary tract, circulatory system and biliary tract). In the mechanism of action of drotaverin, the effect on phosphodiesterase plays a role, causing an increase in the concentration of cAMP and and a decrease in the concentration of calcium ions in the cell. After oral administration, the drug is well absorbed from the gastrointestinal tract. It is metabolized in the liver. It is excreted mainly in the urine and to a lesser extent in the bile.
Indications
Smooth muscle spasm conditions associated with biliary tract diseases: cholelithiasis, cholecystitis, cholecystitis, cholangitis, cholangitis, Vater's papillitis. Spasmodic conditions of the smooth muscles of the urinary tract: kidney stones, ureteral stones, inflammation of the renal pelvis, cystitis, painful urinary urgency. Supportively in spasmodic conditions of smooth muscles of the gastrointestinal tract: peptic ulcer disease of the stomach and duodenum, gastritis, enteritis, colitis, spasmodic conditions of the gullet and pylorus of the stomach, irritable bowel syndrome, spastic constipation and intestinal flatulence, pancreatitis; in spasmodic conditions of the reproductive tract: in painful menstruation, inflammation of the appendages, severe labor pains, threatened miscarriage; in headaches of vascular origin.
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4.3 ★★★★★
Based on 5 reviews
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Product Reviews
★★★★★ 5
Love this stuff!
Style: SPF 50
I use this every day and I love how it is frangrance free and creamy. I have a very fair complexion and I will say it leaves a slight white cast but it doesn’t bother me because it almost makes my fairness more creamy looking. My skin texture has improved since wearing it daily and no allergies from it. I highly recommend especially if you have fairer skin otherwise it may leave a cast .
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Reviewed in the United States on February 19, 2023
★★★★★ 5
Excellent mineral sunscreen with minimal white cast.
Style: SPF 50
This is one of the healthier sunscreens I’ve found so far. You’re not likely going to find a mineral sunscreen that doesn’t leave some white cast. However, this one rubs in pretty good with minimal cast.
You can dab on and rub in fairly easily… as long as you don’t use too much the white cast should be minimal. I am not sure how well this would work on darker skin tones. My arms are a medium skin tone… my legs are more of a light-medium tone.
I prefer mineral sunscreens, and this is the best one I found so far and compatible to Supergoop mineral play. If you liked that one, you would likely enjoy this Coola one too.
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Reviewed in the United States on January 25, 2025
★★★★★ 1
Would not recommend
Style: SPF 50
I literally never write reviews but felt compelled to write one for this sunscreen because I was very caught off guard by all the positive reviews. This sunscreen leaves the most insane white sheen that never soaks in and gets on EVERYTHING. I put this on and drove to the beach and had sunscreen on my car seat, the steering wheel, the center console, the door, EVERYWHERE!
It took forever to clean up and was such a hassle and that was after having let the sunscreen soak into my skin for an hour.
Also the sunscreen is really thick and difficult to spread and makes you look ghostly white. Plus, the sunscreen has a really odd odor that reminded me of play dough? That might not be a negative thing for everyone but I found it unpleasant.
There are definitely better mineral sunscreens out there. For the price I expected a much better product.
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Reviewed in the United States on June 11, 2025
★★★★★ 3
Sticky and white
Style: SPF 50
The sunscreen has a very sticky and thick texture. It will keep you from getting sunburnt, but it will also leave you with a white color.
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Reviewed in the United States on July 22, 2024
★★★★★ 4
Good sunscreen
Style: SPF 50
Super good coverage and it lasts a long time in the sun and even through water activities. The only negative is the white cast. Not as bad as others but just be aware it doesn’t fully rub in.
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Reviewed in the United States on May 1, 2025
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