SKU: 29314404098

Methylfolate - 5 mg, 60 Capsules

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Description

Methylfolate - 5 mg, 60 CapsulesFolate is a vital B vitamin that plays a key role in methylationa critical process for DNA synthesis, detoxification, neurotransmitter production, and cardiovascular health. Our formula delivers 5 mg of Quatrefolic, the most advanced and bioavailable form of folate, designed to bypass genetic polymorphisms (such as MTHFR) that impair folic acid metabolism.* Why Quatrefolic? Quatrefolic is the glucosamine salt of (6S) 5 methyltetrahydrofolatethe

Folate is a vital B vitamin that plays a key role in methylation—a critical process for DNA synthesis, detoxification, neurotransmitter production, and cardiovascular health. Our formula delivers 5 mg of Quatrefolic®, the most advanced and bioavailable form of folate, designed to bypass genetic polymorphisms (such as MTHFR) that impair folic acid metabolism.*

Why Quatrefolic®?

Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate—the bioactive form of folate that the body uses directly, without requiring conversion. Unlike folic acid, which must go through multiple enzymatic steps to become active, Quatrefolic® is ready for immediate uptake and use at the cellular level.*

  • Clinically studied for enhanced bioavailability
  • Supports methylation pathways*
  • Supports healthy homocysteine balance*
  • Supports mood and cardiovascular health*
  • Essential for fetal development and reproductive health*

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Who It's For

This high-dose formula is ideal for individuals with increased folate needs or those with MTHFR gene variants who may have trouble converting folic acid to its usable form.*

How It Works

Folate is required to convert homocysteine into methionine—a process vital for cardiovascular and neurological function. It also supports the production of neurotransmitters like serotonin, dopamine, and norepinephrine, which influence mood and cognition.*

What Makes Ours Better?

  • Longevity Focused: We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*
  • Triple Lab Tested: Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.
  • Complete Transparency: In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body. 
  • USA Manufacturing Excellence: Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

1 Bani Soheila, J Caring Sci 2013 
2 Mazza A. et al. Biol Regul Homeost Agents 2016
3 Rima Obeid R., Herrmann W. FEBS Letters 580, 2006
4 Stover Patrick, Curr Opin Biotechnol 2017
Seshadri S. at al. N Engl J Med 2002 
6 Bottiglieri T, J Neurol Neurosurg Psychiatry 2000 
7 Thaler C.J. 2014 
8 Stover PJ. Modern Nutrition in Health and Disease 2012
9 Tinelli C, Di Pino A Front. Nutr. 2019

Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 8,500 mcg DFE** (5 mg) 2,125%
* Daily Value (DV) **DFE (Dietary Folate Equivalent) 
REV. 10.24 
  • OTHER INGREDIENTS: Vegetable cellulose (capsule), cellulose.
  • SUGGESTED DAILY USE: Take one (1) capsule daily, or as directed by your healthcare professional.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18 or are undergoing treatment for a
    medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 29314404098

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Judie Edwards
Fort Morgan, US
★★★★★ 5
Not stiff or tight…
Size: 13.5 Little Kid, Color: Turquoise/Multi
My niece loved them. So many of the slips in shoes are too stiff and tight, this one was easy on, not stiff or tight, just perfect!
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Reviewed in the United States on March 18, 2026
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Chelsea, US
★★★★★ 5
Great for the price and the rhinestones add the extra pop.
Size: 2 Big Kid, Color: White/Rhinestones
My 7yo loves them. They appear well made and fit as expected. I saw some reviews of them being too big but no issues here. She’s worn them everyday for a week and she said they are comfortable. Color matches description and the rhinestones add the “extra sparkle” she loves. They did get some mud on them at recess but it was easy to clean off. Overall, no complaints for the price.
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Reviewed in the United States on October 3, 2025
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Amazon Customer
Draper, US
★★★★★ 5
Great shoe
Size: 5 Big Kid, Color: White/Rhinestones
Price is right, attractive looking shoe
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Reviewed in the United States on June 9, 2026
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Lord Prince
San Leandro, US
★★★★★ 5
Inexpensively Cute, Resilient and Durable...
Size: 5 Big Kid, Color: Purple, Size: 5 Big Kid, Color: Purple
Purchased these cheap mesh-like breathable, high quality light-weight canvas material non-reputable, off-brand name sneakers for my stepdaughter because her puma sneakers were wet. My daughter loves them; not only are they her favorite color, she says they're very comfortable and easy to put on. They're easy to put on, with a slip on style and also have tie up for a tighter fit. My daughter also says likes the purple in-sole bubble that looks like a real air bubble but its really hard plastic volcanized to give a nice polished purple color finish. My daughter is happy with them, so I am too. They're well worth the practical cost, I look forward to them lasting a growth period of approximately six months to a year. Highly recommended. Pick you child's favorite color! You'll be happy you did...
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Reviewed in the United States on April 30, 2025
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Amazon Customer
Boise, US
★★★★★ 4
Worth the buy so far!
Size: 4 Big Kid, Color: Gradient Blue
So far my child lives this shoes. They are comfortable and stylish for her!
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Reviewed in the United States on April 5, 2026

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