Nicotinamide Riboside Pro 1000 - 90 capsules

Supercharge NAD+ with Clinical Strength NR

• Rapidly boosts NAD+ levels*^1-3,5,6,8
• Enhances cellular energy production*^1-3,5,6
• Promotes DNA repair & stability*^1-3,5,6
• Supports brain & heart health*^1,3,4-7
• Helps combat the effects of aging*^1,3,4,6

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Next-Level Cellular Support

Nicotinamide Riboside (NR) is a cutting-edge breakthrough in longevity science. As a powerful vitamin B3 derivative and direct precursor to NAD+, NR helps restore declining NAD+ levels—revitalizing energy production and cellular function across the body’s trillions of cells.*^1,3,6

Each serving of NR Pro 1000 delivers a full clinical dose of ultra-pure NR—the same strength used in key human studies on NAD⁺ restoration and healthy aging. Once reserved for physicians and elite athletes, this powerful level of support is now available to anyone seeking serious, science-backed rejuvenation.*¹²

Pioneering Longevity Since 1988

For over 36 years, ProHealth has been dedicated to crafting the world’s highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do.

More NAD+. More Energy.

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell of your body, essential for converting nutrients into energy, activating DNA-repair enzymes (PARPs), and regulating sirtuins—proteins that influence gene expression and longevity. As a cornerstone of cellular metabolism, NAD+ supports energy production, DNA integrity, and healthy aging.*^1,3-5,6

By middle age, NAD+ levels in some tissues can drop by up to 50%, slowing down cellular repair and metabolic efficiency. One of the most effective ways to maintain NAD+ is with Nicotinamide Riboside (NR)—a clinically studied form of vitamin B3 that supports the body’s natural NAD+ production pathways, helping you feel energized, resilient, and more youthful as you age.*^1,3-5,6

Why NR Stands Apart

• The Gold Standard: Nicotinamide Riboside (NR) is the ultimate NAD+ precursor, serving as an essential building block in the NAD+ synthesis pathway*^1,3,4
• Scientifically Supported: A form of vitamin B3, NR has undergone extensive clinical testing, demonstrating both efficacy and a strong safety profile*^1,3,5,6,8
• 37 Trillion Benefits: NAD+ fuels energy production in trillions of cells, supporting the health and function of every vital organ in the body*^1,3,6,7
• Rapid Results: NR starts boosting NAD+ levels within 24 hours, with substantial increases observed over days to weeks in a dose-dependent manner*^1,3,6,8

The ProHealth Difference

• Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
• Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
•  Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.
• Manufactured in the USA: Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.
• 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.

Supercharge NAD+ with Clinical Strength NR

Rebuild Your Body’s NAD+ Supply—Daily*

To maintain peak performance, your body requires a steady supply of NAD+. With NR, you can effortlessly and continuously support your NAD+ levels. Research demonstrates that supplementing with NR can elevate NAD+ levels in a dose-dependent manner, meaning higher doses yield greater increases in NAD+ concentrations.*^1,3,6,8

Fuel Cellular Energy Production*

NAD+ plays a vital role in converting food into usable energy at the cellular level. With NR, you can optimize ATP production, leading to enhanced energy availability throughout the body. This boost in cellular energy not only supports physical performance but also contributes to enhanced quality of life.*^1,3,6

Target All 12 Hallmarks of Aging*

As we age, NAD+ levels naturally decline, making replenishment essential to support core longevity processes. NAD+ targets the root causes of aging, fueling essential enzymes like PARPs, which repair DNA and maintain cellular integrity, and activating Sirtuins, which regulate gene expression, inflammation, and stress response—key contributors to healthy aging.*^1,3,4,6

A Word from our Chief Science Officer

“Raising NAD+ levels is all about delivering niacin equivalents—the molecular building blocks your body uses to generate NAD+. Nicotinamide riboside has long been a standout for its proven results and strong clinical foundation. Now, next-generation forms like NR hydrogen malate (NRHM) are taking the science even further. With improved stability, robust safety data, and the added metabolic benefits of malic acid, NRHM represents a significant advancement in NAD+ support—and one of the most promising innovations in the field today.”

100-Day Risk-Free Guarantee

We’re confident you’ll feel the difference. But if you’re not completely satisfied, simply return the bottle within 100 days—no questions asked.

The Global Leader in NAD+ Support

ProHealth offers the world’s most comprehensive collection of NAD+-boosting supplements. From foundational ingredients like NR and NMN to next-generation compounds such as NMNH and Apigenin, our lineup spans every major pathway involved in NAD+ production and preservation. With multiple delivery forms, clinically studied ingredients, and advanced formulations designed to target energy, metabolism, brain health, and longevity, ProHealth is the global leader in NAD+ support—trusted by health seekers, researchers, and practitioners alike.*

• Nicotinamide Riboside (NR): A vitamin B3 derivative and essential precursor in the NAD+ production pathway.*

References:

1. Orr ME et al. GeroScience. 2024;46(1):665-682.
2. Mehmel M et al. Nutrients. 2020;12(6):1616.
3. Nascimento EBM et al. J Clin Endocrinol Metab. 2021;106(5):1437-1447.
4. Vreones M et al. Aging Cell. 2023;22(1):e13754.
5. Elhassan YS et al. Cell Rep. 2019;28(7):1717-1728.e6.
6. Martens CR et al. Nat Commun. 2018;9(1):1286.
7. Damgaard MV et al. Sci Adv. 2023;9(29):eadi4862.
8. Trammell SAJ et al. Nat Commun. 2016;7(1):12948.
9. Nour V et al. Compositional characteristics of fruits of several apple cultivars. 2010
10. Schabert G et al. Molecules. 2021;26(9):2729.
11. Dziwenka M et al. Toxicol Res Appl. 2022;6:23978473221108881.
12. Based on registered ongoing or completed clinical trials under "nicotinamide riboside" on clinicaltrials.gov.