SKU: 57825988339

Sirtuin 6 Activator - 60 capsules

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Description

Sirtuin 6 Activator - 60 capsulesSirtuin 6 Activator: Inspired by the Blue Zones Activates sirtuin 6 (SIRT6)1,4,6,7* Provides Blue Zone bioactives*5,6 Supports multiple longevity pathways*5 Neutralizes free radicals*5,12 Supports a healthy immune system & inflammatory response* 8,5,9 11 View Certificate of Analysis Not all fucoidan is created equal. After three years of extensive research and testing, we've finally sourced an authentic Fucus vesiculosusa special type of seaweed

Sirtuin 6 Activator: Inspired by the Blue Zones

  • Activates sirtuin 6 (SIRT6)1,4,6,7*
  • Provides “Blue Zone” bioactives*5,6
  • Supports multiple longevity pathways*5
  • Neutralizes free radicals*5,12
  • Supports a healthy immune system & inflammatory response* 8,5,9-11

View Certificate of Analysis

Not all fucoidan is created equal. After three years of extensive research and testing, we've finally sourced an authentic Fucus vesiculosus—a special type of seaweed renowned for its powerful fucoidan content and abundant marine polyphenols. This premium seaweed extract sets a new benchmark in longevity science.* 2,5,8,13,21,22,25

What Makes Ours Better?

  • Fucoidan-Rich Seaweed: We deliver pure, concentrated seaweed—not synthetic compounds or low-quality extracts—packed with fucoidan, a potent SIRT6 activator.*21,22
  • Longevity Boost: Each serving provides a full 400mg dose of fucoidan, the scientifically-backed compound for healthy aging.*
  • Full Spectrum Support: Our formula blends whole-plant seaweed powder with high-potency extracts, offering a more complete range of bioactive compounds to amplify fucoidan’s anti-aging potential.*12,15
  • Maximized Bioactivity: Unlike many seaweed extracts that lose potency through harsh processing, our fucoidan is gently extracted using a specialized water-based method, preserving its full molecular structure for optimal effectiveness.*5

Why Choose ProHealth?

  • Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
  • Triple Lab Tested: Subjected to three rounds of independent third-party lab testing to ensure unmatched potency and purity.
  • Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.
  • Manufactured in the USA: Made in FDA-regulated, GMP-certified facilities, adhering to the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We’re confident you’ll love our product. If you’re not satisfied, contact our Santa Barbara, CA office for a full refund within 100 days—no hassle, no questions asked.

Not all fucoidan is created equal.

For centuries, Japan—home to one of the world’s longest-living populations—has relied on seaweed as a dietary staple, prized for its powerful antioxidants and cellular-protective compounds. Research consistently links regular seaweed consumption to enhanced health and longevity, reinforcing its vital role in healthy aging.*15

Building on this tradition, Sirtuin 6 Activator delivers fucoidan, one of seaweed’s most potent bioactive compounds. Naturally found in the cell walls of brown seaweed, fucoidan is clinically recognized for its ability to activate SIRT6, a key enzyme that supports healthy aging at the cellular level.*1


By activating SIRT6, this fucoidan-rich formula goes beyond simple antioxidant support to revitalize cellular health at its core. Research shows that increased SIRT6 activity can aid in DNA repair, boost genomic stability, and support a healthy systemic inflammatory response—processes linked to longevity in Blue Zone populations.*5,8,9,12,14,16

Emerging studies further suggest that higher SIRT6 activity correlates with longer lifespans in multiple animal species. Scientists are now exploring its potential for brain aging, heart health, and overall longevity, with human trials underway to further uncover its impact on healthy aging.*20,26-28


Sirtuin 6 Activator: Inspired by the Blue Zones

Aging is associated with cellular changes, including DNA damage, inflammation, and metabolic shifts, all of which have been studied in relation to SIRT6’s biological functions. Research suggests that SIRT6 plays a role in key cellular processes that support overall health.*

  • Supports DNA Repair – SIRT6 stabilizes the genome by repairing double-strand breaks and maintaining telomere integrity, reducing genetic instability, a major hallmark of aging.*6
  • Influences Metabolic Balance – SIRT6 shifts cells away from inefficient sugar metabolism and toward fat oxidation, mimicking the anti-aging effects of caloric restriction.*17
  • Clears Senescent Cells – Fucoidan acts as a potential senolytic, helping the body remove dysfunctional cells that drive aging.*4,13,19
  • Protects Mitochondria – SIRT6 supports healthy cellular energy production, safeguarding from oxidative stress so cells can generate energy efficiently.*5

Neutralizes Free Radicals*

Oxidative stress occurs when free radicals accumulate and damage cells, proteins, and DNA—a primary driver of aging. ProHealth Sirtuin 6 Activator combats oxidative damage through multiple pathways:

  • Directly Scavenges Free Radicals – Fucoidan’s unique sulfated polysaccharide structure binds to and neutralizes reactive oxygen species (ROS) before they can harm cells.*12
  • Provides Antioxidant Support – This formula combines fucoidan with polyphloroglucinols, marine polyphenols that strengthen cellular defenses against oxidative damage.*5
  • Enhances Cellular Antioxidant Pathways – By enhancing glutathione and superoxide dismutase (SOD) levels, SIRT6 supports the body’s natural ability to maintain oxidative homeostasis.*12

Supports a Healthy Immune System & Inflammatory Response*

Healthy immune system and inflammatory responses are essential for long-term health and longevity. Research suggests that fucoidan and SIRT6 may help support immune function and inflammation balance through multiple pathways:

  • Supports Immune Cell Activity – Fucoidan supports the activity of macrophages, natural killer (NK) cells, and lymphocytes, helping to maintain a robust immune system and clear damaged cells.*5,8,10
  • Helps Maintain a Healthy Inflammatory Response – SIRT6 influences cytokine activity and inflammatory response mechanisms, helping to support healthy inflammation for optimal aging.* 5,8,9
  • Enhances Gut-Immune Function – Fucoidan supports a healthy gut microbiome, which is closely linked to immune and inflammatory balance.*11

Order now and join the 200,000+ people who trust ProHealth Sirtuin 6 Activator for their cellular health!

Ingredients:

  • Brown Seaweed (Fucus vesiculosus): A rich source of fucoidan, a bioactive polysaccharide recognized for supporting cellular health and activating SIRT6, the longevity enzyme.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

  1. Rahnasto-Rilla M et al. Mar Drugs. 2017;15(6):190.
  2. Kawaguchi T et al. Int J Oncol. 2015;46(5):2216-2222.
  3. Yu W et al. Mol Nutr Food Res. 2017;61(10):1700136.
  4. Cao L et al. Mar Drugs. 2020;18(11):564.
  5. Li B et al. Molecules. 2008;13(8):1671-1695.
  6. López-Otín C et al. Cell. 2023;186(2):243-278.
  7. Iso H and Kubota Y. Asian Pac J Cancer Prev. 2007;8 Suppl:35-80.
  8. Jayawardena TU et al. Mar Drugs. 2022;20(12):755.
  9. Apostolova E et al. Polymers. 2020;12(10):2338.
  10. Bogolitsyn K et al. Plant Foods Hum Nutr. 2024;79(2):511-517.
  11. Luthuli S et al. Mar Drugs. 2019;17(9):487.
  12. Catarino MD et al. Mar Drugs. 2018;16(8):249.
  13. Zhang L et al. Innov Aging. 2022;6(Suppl 1):130.
  14. Myers S et al. Biol Targets Ther. 2011;45.
  15. Myers S. Biol Targets Ther. 2010;33.
  16. Li X et al. Front Cell Dev Biol. 2021;9:641315.
  17. Zhang N et al. Cell Cycle. 2016;15(7):1009-1018.
  18. Chilton WL et al. PLoS ONE. 2014;9(4):e92088.
  19. Akter R et al. Int J Mol Sci. 2021;22(8):4180.
  20. Zhang L et al. Innov Aging. 2022;6(Suppl 1):130.
  21. Gorbunova V. Innov Aging. 2019;3(Suppl 1):S8.
  22. Kawamura A et al. Mar Drugs. 2021;19(8):452.
  23. Willcox DC et al. Ann NY Acad Sci. 2009;1173:126-138.
  24. Buettner D. Natl Geogr Books. 2015.
  25. Korotkov A et al. Trends Cell Biol. 2021;31(12):994-1006.
  26. Zhang L et al. Oxid Med Cell Longev. 2019;2019:8918914.
  27. Yang J et al. Int J Biol Macromol. 2024;277(Pt 3):134397.
  28. Wang K et al. Ther Adv Chronic Dis. 2022;13:20406223221076891.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Fucoidan (from Bladderwrack [Fucus vesiculosus] Whole Plant Extract and Brown Seaweed [Undaria pinnatifida] Whole Plant Extract) 400 mg
Bladderwrack (Fucus vesiculosus) Whole Plant Powder 100 mg
† Daily Value (DV) not established
REV.10.24

  • OTHER INGREDIENTS: Vegetable cellulose (capsule), microcrystalline cellulose, bamboo silica.
    • May contain traces of fish and/or shellfish residue.
  • SUGGESTED DAILY USE: Take one (1) capsule daily, or as directed by your healthcare professional.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 57825988339

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Mimis cake school
Lowell, US
★★★★★ 5
Finally! Comfy pillows for a😴good night sleep
Color: White, Size: Queen (Pack of 4)
Just wow!! Looking for new pillows that are comfortable & hold their shape. These are it ! I love anything by utopia. And these pillows did not disappoint. Great value. Feels like a high end pillow. As a side sleeper these are a keeper. Highly recommend. And ill be purchasing more!
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Reviewed in the United States on May 18, 2026
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Jennifer Kuhns
Houston, US
★★★★★ 4
Soft...but fluffy and tall
Color: White, Size: Standard (Pack of 2)
I've only had these pillows for about a week. They are a great quality pillow. The cover is soft and seems well made. My only complaint is that they are VERY full pillows. If you're tall with broader shoulders, you'll probably love them. If you're shorter with a smaller frame you will probably feel like your head is too high and your neck at a weird angle (my problem). There seemed to be mixed reviews about softness....I would consider these a nice medium pillow. Soft filling but firm enough that your head doesn't sink to the bed. Definitely NOT a down-like pillow, so if that's what you're looking for, this is not for you.
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Reviewed in the United States on April 10, 2026
M
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Maria Fernanda Rojas Mejia
Lowell, US
★★★★★ 5
Soft, fluffy and surprisingly comfortable
Color: White, Size: Queen (Pack of 2), Color: White, Size: Queen (Pack of 2)
I really liked these pillows. I tried to show different things in my photos because I wanted people to see the details: the design, how fluffy they are, and how full and thick they actually look. They are so full that the pillowcase even looks tight once you put it on, which I actually loved because they look luxurious and well-filled. At first glance they look very thick and high, but once you lay down they feel soft and fluffy instead of hard. They adjust comfortably and feel very cozy whether you’re sleeping, relaxing, or even reading before bed. I think they offer a really good balance because they feel supportive without being stiff. Of course, pillow preference is very personal—some people like lower pillows and others like higher ones—but for someone who likes fuller pillows that are still soft and comfortable, these are great. They are spacious, cozy, and feel like a very good purchase overall. I honestly don’t have any complaints so far. Definitely happy with them.
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Reviewed in the United States on May 15, 2026
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RF
Phoenix, US
★★★★★ 5
Great quality pillows. Very difficult wrapping.
Color: White, Size: King (Pack of 2)
The Pillows are the real deal. Very fluffy but with good support. I was surprised by the weight of the box they came in, pretty heavy so you know there’s good quality pillows inside. The one negative is that the pillows are packed in very very tight plastic because they come compressed. But the thing is, it’s really a chore to open them. You have to be careful not to cut through the plastic to the material, but the plastic is put on so incredibly tight that it’s even hard to get your finger underneath. But I found a way to open them. Near the top, insert A very flat metal ruler as far in as you could get it. Then cut through the plastic that’s above the metal ruler. That prevents a sharp tool from damaging the pillows. As you get through the plastic above the ruler, keep pushing the ruler further down into the package. Believe me, this simplifies what could be a very difficult unpacking. I am very surprised that the company that makes them does not insert the type of opener that you find on boxes you receive in the mail or even packages that you get from the grocery store where you just pull a tab and that opens the package. These are really good pillows, but you must be very careful about using a sharp object when opening the box and when trying to cut through the plastic. I am a strong man and have the tools needed, a very flat metal ruler, and a box cutter, knife, or razor. Good luck. !!
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Reviewed in the United States on May 5, 2026
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Verified Purchase
Starr Charles
Pawtucket, US
★★★★★ 5
These hold up very well
Color: White, Size: Standard (Pack of 2)
I have NO luck with pillows. I’ve been in stores & tried them. They seemed ok there. At home, nope. I’ve been getting headaches & neck aches from lousy pillows. I’ll change one, a few nights relief. It doesn’t help that I’m prone to headaches. After reading about different pillows, I settled on these. The reviews were better than so many different ones I was looking at. Including high priced & brand names. I bought the standard size. When I saw, “Customers Usually Keep This”, I kept my fingers crossed. When I received them, I took one out of the package & put my head on it & thought, oh no! This is too hard! I tried it again. Ok….. I slept on it & haven’t had any pains since. It’s soft but firm enough to keep my head from sinking & messing up my neck. I don’t move. No more flipping my pillow over. My head doesn’t go below my neck anymore! This has been 2 months now, but it hasn’t changed at all. I wake up happy, not complaining. No more pains or headaches. This saved me from losing days with a heating pad or an ice pack. The price was excellent for 2 pillows. I can’t believe a blind buy was the answer! These are incredible. Finally, something worked for me.
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Reviewed in the United States on May 13, 2026

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