Pay in installments of $17.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 3 - Sep 8
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
PE-Cy7 Armenian hamster Anti-Mouse CD11c Antibody (S-R518)Product Specification Host Armenian hamster Antigen CD11c Synonyms Integrin alpha X; CD11 antigen like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax Location Membrane Accession Q9QXH4 Clone Number S R518 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation PE Cy7
Product Specification
| Host | Armenian hamster |
| Antigen | CD11c |
| Synonyms | Integrin alpha-X; CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax |
| Location | Membrane |
| Accession | Q9QXH4 |
| Clone Number | S-R518 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | PE-Cy7 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Ms |
Background
CD11c, also known as integrin alpha X (ITGAX), is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with the 95 kDa beta2 integrin CD18 to form the αXβ2 heterodimer (complement receptor 4, CR4), which mediates cell adhesion, migration, and phagocytosis by binding diverse ligands such as iC3b, fibrinogen, ICAMs, and denatured proteins; it is predominantly expressed on myeloid dendritic cells, tissue macrophages, activated monocytes, and some B-cell subsets, serving as a classic marker for conventional dendritic cells in both mice and humans, and plays crucial roles in immune surveillance, antigen presentation, and inflammatory responses while also being implicated in autoimmune diseases and serving as a therapeutic target in cancer immunotherapy.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy