Pay in installments of $26.25 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 8 - Sep 13
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Mouse Anti-Rat CD47 Antibody (S-3836)Product Specification Host Mouse Antigen CD47 Synonyms Leukocyte surface antigen CD47; Integrin associated protein (IAP); Cd47 Location Cell membrane Accession P97829 Clone Number S 3836 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Rt Positive Sample SD Rat splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date
Product Specification
| Host | Mouse |
| Antigen | CD47 |
| Synonyms | Leukocyte surface antigen CD47; Integrin-associated protein (IAP); Cd47 |
| Location | Cell membrane |
| Accession | P97829 |
| Clone Number | S-3836 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Rt |
| Positive Sample | SD Rat splenocytes |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:200 | Rt |
Background
CD47 is a ubiquitously expressed transmembrane glycoprotein that serves as a critical “don’t-eat-me” signal by engaging signal-regulatory protein α (SIRPα) on macrophages and dendritic cells, thereby inhibiting phagocytosis and bridging innate and adaptive immunity; beyond immune evasion, CD47 modulates integrin activation, cell adhesion, migration, apoptosis, and metabolic signaling, and its marked over-expression on diverse tumor cells—driven by oncogenic pathways such as KRAS-PI3K-STAT3, hypoxia-HIF-1α, or amino-acid-mTOR cascades—correlates with reduced patient survival, making blockade of the CD47–SIRPα axis a promising therapeutic strategy to restore anti-tumor immunity.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy