SKU: 11089664357

EphA10 His Tag Protein, Human

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Description

EphA10 His Tag Protein, HumanProduct Specification Species Human Antigen EphA10 Synonyms Ephrin type A receptor 10, EPHA10 Accession Q5JZY3 Amino Acid Sequence Glu34 Ala565, with C terminal 10*His

Product Specification


Species Human
Antigen EphA10
Synonyms Ephrin type-A receptor 10, EPHA10
Accession Q5JZY3
Amino Acid Sequence

Glu34-Ala565, with C-terminal 10*His EEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPAGGGSGGGSHHHHHHHHHH
Expression System HEK293
Molecular Weight 68-90kDa
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Jing Peng, Danhua Zhang. Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration, J Investig Med. 2021 Aug;69(6):1215-1221. Epub 2021 May 14.
2. Kullander K., Klein R. Mechanisms and functions of Eph and ephrin signalling. Nat. Rev. Mol. Cell Biol. 2002;3:475-486.
3. Dodelet V.C., Pasquale E.B. Eph receptors and ephrin ligands: Embryogenesis to tumorigenesis. Oncogene. 2000;19:5614-5619.
4. Aasheim H.C., Patzke S., Hjorthaug H.S., Finne E.F. Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis. Biochim. Biophys. Acta. 2005;1723:1-7.
5. Nagano K., Maeda Y., Kanasaki S., Watanabe T., Yamashita T., Inoue M., Higashisaka K., Yoshioka Y., Abe Y., Mukai Y., Kamada H., Tsutsumi Y., Tsunoda S. Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers. J. Control Release. 2014;189:72-79.

Background

Ephrin receptors (Ephs), the largest subfamily of receptor tyrosine kinases, are known to modulate cell–cell signaling by interacting with cells’ membrane-bound ephrin ligands on neighboring cells, thereby regulating tissue organization, vascular development, and progression of many diseases including cancer. Ephrin receptor A10 (EphA10), a member of the Eph subfamily, is not expressed in normal human adult tissue except in the testis. The Eph/ephrin signaling mediates cell-cell interaction and contributes to the tumorigenesis, angiogenesis and metastasis in many cancers. EphA10 expression is common in malignant cells across histology of various tumors and has been associated with poor prognosis in patients with breast, prostate, and gallbladder cancers.

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SKU: 11089664357

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4.2 ★★★★★
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Tonyamazin
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★★★★★ 5
Great comfortable, pillows.
Color: Black(4pack), Size: Standard
These are some great, comfortable pillows. They are soft and feel great. They are good for sleeping on or just using them to be comfortable in bed.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 23, 2026
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George Mann
Fort Morgan, US
★★★★★ 5
Enjoyable
Color: Grey, Size: Queen
Holds their shape and stay cool.
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Reviewed in the United States on May 24, 2026
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River
Waukegan, US
★★★★★ 5
So comfy
Size: King (Pack of 1), Style: Standard Loft (4" - 5")
I spent time looking up/watching videos on pillows for neck pain and this one comes up a lot. I’m someone that used to wake up every few weeks with a stiff neck so bad it could make me cry at work. I haven’t had that happen once after months of using this pillow. I look forward to laying my head down on it every night. It’s a luxury experience every time. I think what it does so well is maintain its shape. You can really squish it up how you want and it stays there even after hours. Moldable but somehow still firm. It’s expensive but to me the value is there because I no longer get crazy neck pain from sleep. Worth trying it out for sure. Btw I was stuck between this is and Purple brands couple top end options. I never got around to trying them because I tried this one first and was very satisfied! Feb 2026. Still use it every night and it's still protecting me from neck pain I used to get from sleeping. It's held up amazing. Hope to use it for many more years.
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Reviewed in the United States on January 18, 2025
A
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Amazon Customer
Dallas, US
★★★★★ 5
Saatva Pillow is great
Size: Standard/Queen (Pack of 1), Style: Standard Loft (4" - 5")
So far this is the best pillow I have had in the last 10 years and I have tried two Purple pillows a couple different memory foam and Gel pillows at least 4 more pillows that I can't even remember the names of. My neck and shoulders are almost pain free. I have also been doing more stretching of my arms which is also helping, but this pillow has really made the most difference in the pain I have had, I felt difference from the first time I put my head on it. It's comfortable, the perfect height I got the 4"-5", I also got the queen size and it's great. It supports my head just right. I also ordered the Saatva Classic 14" mattress from the company and I sure hope it's as good or better would be great because I have back issues for the last 50 years.
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Reviewed in the United States on September 16, 2025
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YL
Lake Worth, US
★★★★★ 1
Cotton Fluff Around a Mostly Empty Bag
Size: King (Pack of 1), Style: High Loft (6"-7")
Bought the high-loft king, thinking it would be a great (tall) side-sleeper. What I got? A very nice, completely compressible cotton outer shell wrapped around a bag a bit smaller than a standard pillow. In that bag? A tiny amount of small latex chunks, just about a third full. That’s right, some cotton fluff around a basically empty bag. Could you buy some latex yourself and add it? No, the bag is sewn shut. You could probably fill a small pillow with latex you bought elsewhere and put that in. But seriously, what did you pay Saatva for in that case? Probably as close as I’ve seen a major/high-reputation company get towards a literal example of rip off.
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Reviewed in the United States on May 31, 2026

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