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Description
CDH17/LI-cadherin His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Antigen CDH17 LI cadherin Synonyms Cadherin 17, HPT 1 Accession XP_005563762. 2 Amino Acid Sequence Gln23 Met787, with C terminal 10*His
Product Specification
| Species | Cynomolgus |
| Antigen | CDH17/LI-cadherin |
| Synonyms | Cadherin-17, HPT-1 |
| Accession | XP_005563762.2 |
| Amino Acid Sequence | Gln23-Met787, with C-terminal 10*His QEGKFSGPLKPMTFSIYEGQEPSQIIFQFKANPPAVTFELTGETDNIFKIEREGLLYYTKALDRETRSTHNLQVAALDANGAIVEGPVPITIEVKDVNDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLSYQIVIQLPMINNVMYFQINNKTGGISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPEPVEMVENSTDPHPIKITQVRWNDPGAQYSLVDKEKLPRFPFSIDQEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVQDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDSDEENTANSLLNYRIVEQTPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNVGSTILTIQATDADEPFTGSSKILYHVIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAISNIVFKAENPEPLVSGVTYNASSFAKFTLFVTDVNEAPEFSQYVFQAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSQFHLILTDVNDNPPRLAKDYMDLYFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSIASESLQNDWQVSKINGTHARLSTRHTDFEEKEYVVSIRINDGGRPPLESTVSLTVTFCSCGEDGCFRPAGHQPGIPTVGMGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 95-110kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1. Chen R ,Cao J ,Chen J , et al.Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma[J].World Journal of Gastroenterology,2012,18(48):7251-7261. 2. Long Z ,Zhou M ,Fu J , et al.Association between cadherin-17 expression and pathological characteristics of gastric cancer:A meta-analysis[J].World Journal of Gastroenterology,2015,21(12):3694-3705. |
Background
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily,genes encoding calcium-dependent,membrane-associated glycoproteins.Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region,7 cadherin domains,and a transmembrane region but lacking the conserved cytoplasmic domain.Cadherins preferentially interact with themselves in a homophilic manner in connecting cells;cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine.It's also involved in intestinal peptide transport.
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