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Description
Mouse CD4, His tagProduct Specification Species Mouse Synonyms T cell differentiation antigen L3T4, T cell surface antigen T4 Leu 3 Accession P06332 Amino Acid Sequence Protein sequence(P06332, Lys27 Thr394, with C 10*His)
Product Specification
| Species | Mouse |
| Synonyms | T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3 |
| Accession | P06332 |
| Amino Acid Sequence | Protein sequence(P06332, Lys27-Thr394, with C-10*His) KTLVLGKEGESAELPCESSQKKITVFTWKFSDQRKILGQHGKGVLIRGGSPSQFDRFDSKKGAWEKGSFPLIINKLKMEDSQTYICELENRKEEVELWVFKVTFSPGTSLLQGQSLTLTLDSNSKVSNPLTECKHKKGKVVSGSKVLSMSNLRVQDSDFWNCTVTLDQKKNWFGMTLSVLGFQSTAITAYKSEGESAEFSFPLNFAEENGWGELMWKAEKDSFFQPWISFSIKNKEVSVQKSTKDLKLQLKETLPLTLKIPQVSLQFAGSGNLTLTLDKGTLHQEVNLVVMKVAQLNNTLTCEVMGPTSPKMRLTLKQENQEARVSEEQKVVQVVAPETGLWQCLLSEGDKVKMDSRIQVLSRGVNQTGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:42.9kDa Actual:53-60kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells. The TCR complex and CD4 bind to distinct regions of the antigen-presenting MHC class II molecule. The extracellular D1 domain of CD4 binds to the β2 region of MHC class II. The resulting close proximity between the TCR complex and CD4 allows the tyrosine kinase Lck bound to the cytoplasmic tail of CD4 to phosphorylate tyrosine residues of immunoreceptor tyrosine activation motifs (ITAMs) on the cytoplasmic domains of CD3 to amplify the signal generated by the TCR.
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4.7 ★★★★★
Based on 13 reviews
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Product Reviews
★★★★★ 4
Good fit for Acura MDX
Size: 8.8" x 9.3" x 1.1"
This is an air cabin filter that will fit many cars, and in my case a 2019 MDX. Since this kind of filter is not doing anything critical like keeping dirt out of an engine, I shop around for non-OEM filters for something that strikes a balance between price versus performance. This filter just filters out dust in a car cabin, and when we’re not in our cars, we don’t have the benefit of an air filter when we are walking around outdoors. At a fraction of the price of an Acura filter, this filter seems to strike that balance. The filter media looks sturdy and is embedded with charcoal to help absorb odors.
Installation is very straightforward in my MDX, and similar in most cars. There is a compartment door inside the glovebox that first must be removed before changing the filter. Pay attention to the direction flow arrow that shows which way the filter should be installed.
Overall I am satisfied with this filter. It is inexpensive, fits perfectly, and seems to do the job just fine. It is definitely worth trying if you are trying to save money.
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Reviewed in the United States on October 12, 2024
★★★★★ 5
These filters do the job
Size: 2Pcs
Fits great in my '08 Accord LX and my '19 Accord Sport 2.0t. They filter air well and are easy to install like any cabin air filter in a Honda. I am pleased. Good value for the price.
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Reviewed in the United States on October 8, 2025
★★★★★ 5
Fit my 2014 Odyssey TE
Size: 8.8" x 9.3" x 1.1"
Comes with printed instructions for those who haven't changed it before. Here is the specific use case from my van.
On my 2014 TE its easy to access behind the glove box, open to usual full open then just push the left and right sides in to allow the glove box to come fully out. It may pop off of the mounts, don't panic it snaps right back on. Then look for the little rectangular panel with two small levers on either side. on the black plastic under the dash that you can now see and access. Press the levers and pull towards you, doing a bit of a wiggle to get it out. Its tight, but it will come out with having to break it. Don't gorilla hands it, it will break.
There is a directional arrow on the filter, which you have to remove from the wrapper before installing. Yes, someone *will* forget that. Reassembly the reverse of removal. Check that video sharing site online if you need visual instructions.
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Reviewed in the United States on September 27, 2024
★★★★★ 5
Fits perfectly, and works great!!
Item Package Quantity: 1
★★★★★ – Great Quality Cabin Filter for the Price
Installed this Puroma cabin air filter in my car and immediately noticed cleaner airflow and less odor coming through the vents.
The activated carbon really helps with smells and dust. Installation was quick and easy, only took a few minutes.
Great value compared to dealership prices. Would definitely buy again.
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Reviewed in the United States on May 26, 2026
★★★★★ 5
Satisfied
Item Package Quantity: 1
Perfect fit for my 2013 crv. Easy to install and great price. No issues with the design.
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Reviewed in the United States on May 26, 2026