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Description
FOXP2 Recombinant Rabbit mAb (S-2342-8)Product Specification Host Rabbit Antigen FOXP2 Synonyms Forkhead box protein P2; CAG repeat protein 44; Trinucleotide repeat containing gene 10 protein; CAGH44; TNRC10 Immunogen Synthetic Peptide Location Nucleus Accession O15409 Clone Number S 2342 8 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu, Ms Positive Sample HEK 293, HeLa, HCT 116, Neuro 2a Predicted Reactivity NHPr, Xe Purification Protein A Concentration 2 mg
Product Specification
| Host | Rabbit |
| Antigen | FOXP2 |
| Synonyms | Forkhead box protein P2; CAG repeat protein 44; Trinucleotide repeat-containing gene 10 protein; CAGH44; TNRC10 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | O15409 |
| Clone Number | S-2342-8 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu, Ms |
| Positive Sample | HEK-293, HeLa, HCT 116, Neuro-2a |
| Predicted Reactivity | NHPr, Xe |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500-1:1000 | Hu, Ms |
| ICC | 1:100 | Hu |
Background
FOXP2 protein is a transcription factor that plays a crucial role in the development and functioning of certain neural circuits related to language and speech production. It is encoded by the FOXP2 gene. Mutations in this gene can lead to speech and language disorders. The protein is expressed in various regions of the brain, including the basal ganglia and the cortex. It helps regulate the expression of other genes involved in the formation of neural connections and the development of motor skills necessary for speech. FOXP2 is also found in other species and is believed to be involved in vocalizations and other forms of communication. Its discovery and study have provided valuable insights into the genetic basis of language and the complex mechanisms underlying human communication abilities.
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