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Description
Angiopoietin-1(277-498) His Tag Protein, MouseProduct Specification Species Mouse Synonyms Angiopoietin 1, AGP1, AGPT, Ang1, ANG 1, ANGPT1 Accession O08538 Amino Acid Sequence Arg277 Phe498, with C terminal His Expression System HEK293 Molecular Weight 28 33kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after
Product Specification
| Species | Mouse |
| Synonyms | Angiopoietin-1, AGP1, AGPT, Ang1, ANG-1, ANGPT1 |
| Accession | O08538 |
| Amino Acid Sequence | Arg277-Phe498, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 28-33kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Yoon J C. et al. (2000) Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol Cell Biol. 20(14): 5343-5349. |
Background
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability.
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4.8 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 5
Dewy, Hydrated Skin
Style: Fresh Rose
This is all you need to know- with all the brands and influencers out there, this is the third time I've bought this. I'm not even tempted to buy the new, possibly less expensive products. I use it all four seasons alone or with my cream makeup as a primer. My skin LOVES it. It doesn't crease, separate, or do anything except make my skin look dewy and protect it from the sun. Great product!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 3, 2025
★★★★★ 5
Multiple benefit travel product
Style: Golden Hour
Love this product as it does three things:
1.Protects my skin with spf
2. Moisturizes my skin
3. Adds a slight transparent color glow
A great travel product: quick, easy and with three benefits.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 1, 2026
★★★★★ 4
Great product, only wish there were more colors
Style: Golden Hour
I love the texture, smell, bottle and lightweight coverage of this product, I love that it’s a natural sunscreen. I only wish that they had an even lighter color. Even this color is too dark for my skin (I’m light skinned but not THAT white) and I have to blend it out with regular sunscreen.
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Reviewed in the United States on August 18, 2020
★★★★★ 1
Disappointed in new formulation
Style: Golden Hour
I have been a loyal customer of Coola’s tinted sunscreen for over five years, purchasing it more than ten times on Amazon. It used to be my absolute favorite product—lightweight, luminous, with a beautiful shimmer and a lovely rose-like scent. Unfortunately, the recent reformulation is extremely disappointing.
The new version has a harsh, overwhelming chemical odor—almost petroleum-like—that is off-putting and unpleasant to wear. It no longer applies the same way, and the coverage and radiance I loved are gone. Worse, I have sensitive skin, and this new formula causes tingling and even a slight burning sensation on my face.
I originally thought I had received a bad batch and even repurchased in another shade, hoping it was just a one-off issue. Sadly, both bottles were the same. This is not the product I once loved, and I’m honestly heartbroken by the change. Unless the original formula is brought back, I can no longer recommend or repurchase.
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Reviewed in the United States on October 2, 2025
★★★★★ 5
I usually don't stick to the same product for this long
Style: Bronze Goddess
I've been using this BB Cream with SPF 30, Tinted Moisturizer Sunscreen & Foundation for years, and that’s saying a lot coming from me, as I usually don't stick to the same product for this long. This one, however, is an exception. It offers everything I need in one: excellent sun protection, a natural tint that evens out my skin tone, and lightweight moisturizing coverage. It blends effortlessly, leaving my skin looking flawless without feeling heavy or greasy. I frequently receive compliments on my skin, and I attribute that to this amazing BB cream. Highly recommended for anyone seeking an all-in-one skincare solution!
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Reviewed in the United States on June 29, 2024
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