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Description
Exodus-2/CCL21 Protein, HumanProduct Specification Species Human Synonyms 6Ckine,Beta chemokine Exodus 2,SLC Accession O00585 Amino Acid Sequence Ser24 Pro134 Expression System E. coli Molecular Weight Approximately 12. 2 kDa, a single non glycosylated polypeptide chain containing 111 amino acids. Purity 97% by SDS PAGE or HPLC. Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer 20 mM PB, with 150 mM NaCl, pH 7. 4. Reconstitution Before use
Product Specification
| Species | Human |
| Synonyms | 6Ckine,Beta-chemokine Exodus-2,SLC |
| Accession | O00585 |
| Amino Acid Sequence | Ser24-Pro134 |
| Expression System | E.coli |
| Molecular Weight | Approximately 12.2 kDa, a single non-glycosylated polypeptide chain containing 111 amino acids. |
| Purity | ＞97% by SDS-PAGE or HPLC. |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 20 mM PB, with 150 mM NaCl, pH 7.4. |
| Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
CCL21 is encoded by CCL21 gene that is located in Chr.9 and shows 21-33% identity to other CC chemokines. This chemokine contains the four conserved cysteines characteristic of β chemokines plus two additional cysteines in its unusually long carboxyl terminal domain. CCL21 is highly expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. It elicits effects by binding with CCR7, having functions of T and B lymphocytes chemotaxis and inhibiting hematopoiesis. Recombinant Human Exodus-2/CCL21 is a 12.2kDa protein containing 111 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines
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