SKU: 44636744885

Biotin Rat Anti-Mouse MERTK Antibody (S-R603)

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Description

Biotin Rat Anti-Mouse MERTK Antibody (S-R603)Product Specification Host Rat Antigen MERTK Synonyms Tyrosine protein kinase Mer; Proto oncogene c Mer; Receptor tyrosine kinase MerTK; Mer; Mertk Location Cell membrane Accession Q60805 Clone Number S R603 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse peritoneal exudates cells Purification Protein G Concentration 0. 5 mg ml Conjugation Biotin Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0.

Product Specification


Host Rat
Antigen MERTK
Synonyms Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; Mer; Mertk
Location Cell membrane
Accession Q60805
Clone Number S-R603
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse peritoneal exudates cells
Purification Protein G
Concentration 0.5 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1μg per million cells in 100μl volume Ms

Background

MERTK, also known as MER proto-oncogene tyrosine kinase, is a type I receptor tyrosine kinase and a member of the TAM (TYRO3, AXL, and MERTK) family. It plays crucial roles in various physiological processes, including cell survival, migration, differentiation, and the phagocytosis of apoptotic cells. MERTK is activated by binding to ligands such as GAS6 and PROS1, which triggers autophosphorylation and downstream signaling through pathways like PI3K/AKT, MAPK, and STAT. This receptor is highly expressed in immune cells like macrophages and dendritic cells, and its activation promotes an anti-inflammatory M2 phenotype in macrophages. In the retina, MERTK is essential for the phagocytosis of rod outer segment fragments by the retinal pigment epithelium. Abnormal expression of MERTK has been linked to several diseases, including retinitis pigmentosa and various cancers, making it a potential therapeutic target.

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SKU: 44636744885

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New Z Land Farms
Phoenix, US
★★★★★ 4
Insightful and Compassionate.
Format: Hardcover
I really love Nedra Glover Tawwab's work. I started with "Set Boundaries, Find Peace" and that opened the gateway to a broader and more helpful healing journey for me. This book, "Drama Fee" was just an evolutionary step in her series and a more in depth dealing with family relationships. The different perspectives for each chapter on how the concept can be applied was/is helpful as it often feels like books of this nature are only telling the black or white way to focus on a relationship. I felt seen and heard that though my familial relationships are unique there are commonalities and in turn ways to approach healing, reconciliation (with oneself and with family), understanding and compassion, to a achieve drama free relationships. As humans we are bread for connection and I appreciate Nedra Glover Tawwab's help in navigating them.
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Reviewed in the United States on June 9, 2025
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Diane Burroughs
West Palm Beach, US
★★★★★ 5
Being Our True Selves In Relationships That Matter
Format: Kindle
Nedra Glover Tawwab is a New York Times bestselling author, a licensed therapist, and a sought-after relationship expert. This book is a therapeutic and educational tool that addresses how to consciously change behaviors you’d rather not have in relationships, specifically, around your family. For those of us who have delved into the self-help book world, this is an in-depth, thorough refresher, focusing on family dynamics. Nedra’s core belief is that relationships contribute to mental health. They can cause you pain or they heal you. She focuses on taking your relationships seriously and teaches the art of having tough but intentional conversations to create positive change. OR you’ll learn how to sever ties when the relationship is unmanageable. None is more influential than the formative years we’ve had with our family of origin. A lot of people lament that not everything is about the family, but yup, so often it’s true. In childhood, most likely we weren’t allowed to be ourselves, so our true selves started to develop when becoming an adult. Like a butterfly using its colossal strength to break out of its chrysalis, we too must use our emotional colossal strength to break out of our childhood mold in order to fly. We are able to have relationships with family on our terms.
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Reviewed in the United States on July 3, 2023
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Athena
Waukegan, US
★★★★★ 5
Read. This. Book.
Format: Kindle
Read this book if you have a dysfunctional family or relationship with family members (including in-laws and extended family). Read this book if you think you don’t. Nedra outlines several different types of familial relationships and how challenging it can be to work through dysfunction or things we have considered normal that are not. Nedra also provides wisdom and tools on how to overcome the many challenges that occur in relationships with family members with gentleness, understanding and realistic observations and advice. Please keep in mind that there will likely be much to unpack from both your childhood and adulthood. It can be an incredibly emotional process in which you might need to take breaks and pauses. However, it is a worthwhile endeavor that will allow you a new, healthier perspective on your relationships with others, and it will cause you to re-evaluate yourself and how you interact with others. This is necessary wisdom for cultivating peace and harmony in your life. I wish fellow readers an eye-opening and heartfelt journey. Be kind and gracious to yourself during this experience and best wishes in creating and living your most authentic life.
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Reviewed in the United States on March 8, 2023
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Cara
Whiting, US
★★★★★ 5
Great!
Format: Hardcover
Love Nedra - I recommend this book to all my clients!
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Reviewed in the United States on January 16, 2026
E
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endrina diaz
Louisville, US
★★★★★ 5
Excelente libro
Format: Paperback
Excelente libro lo recomiendo 👍 llego super bien y en buen estado
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Reviewed in the United States on March 11, 2026

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