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Description
FUNDC1 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen FUNDC1 Synonyms FUN14 domain containing protein 1 Immunogen Synthetic Peptide Location Mitochondrion outer membrane Accession Q8IVP5 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HeLa, T 47D, MCF7, RAW264. 7, mouse brain, C6, rat brain Purification Immunogen Affinity Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Rabbit |
| Antigen | FUNDC1 |
| Synonyms | FUN14 domain-containing protein 1 |
| Immunogen | Synthetic Peptide |
| Location | Mitochondrion outer membrane |
| Accession | Q8IVP5 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HeLa, T-47D, MCF7, RAW264.7, mouse brain, C6, rat brain |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
| IHC-P | 1:200-1:500 | Hu, Ms, Rt |
Background
The FUNDC1 protein, also known as FUN14 domain containing 1, is a mitochondrial protein that plays a critical role in mitochondrial dynamics and cellular respiration. It is involved in various metabolic pathways, including fatty acid metabolism, glycolysis, and oxidative phosphorylation. FUNDC1 is highly expressed in tissues such as the brain and blood, and it is enriched in immune cells like monocytes and neutrophils. The protein is also implicated in immune responses and has been associated with processes such as antigen presentation and the regulation of immune cell functions. Additionally, FUNDC1 has been linked to the detoxification of reactive oxygen species (ROS) and is involved in the metabolism of several vitamins and amino acids.
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