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Description
BAX Recombinant Rabbit mAb (SDT-338-76)Product Specification Host Rabbit Antigen BAX Synonyms Bcl2 L 4 Immunogen Synthetic Peptide Location Cytoplasm, Mitochondrion outer membrane Accession Q07812 Clone Number SDT 338 76 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu, Ms, Rt Predicted Reactivity Bv Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability
Product Specification
| Host | Rabbit |
| Antigen | BAX |
| Synonyms | Bcl2-L-4 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Mitochondrion outer membrane |
| Accession | Q07812 |
| Clone Number | SDT-338-76 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 |
Background
Bax and its homolog Bak are key regulators of the mitochondrial pathway of apoptosis. On cell stress Bax and Bak accumulate at distinct foci on the mitochondrial surface where they undergo a conformational change, oligomerize, and mediate cytochrome c release, leading to cell death [PMID: 27932064].
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