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Description
DLST Recombinant Rabbit mAb (S-2283-10)Product Specification Host Rabbit Antigen DLST Synonyms Dihydrolipoyllysine residue succinyltransferase component of 2 oxoglutarate dehydrogenase complex, mitochondrial; 2 oxoglutarate dehydrogenase complex component E2 (OGDC E2); Dihydrolipoamide succinyltransferase component of 2 oxoglutarate dehydrogenase complex; E2K; DLTS Immunogen Synthetic Peptide Location Nucleus, Mitochondrion Accession P36957 Clone Number S 2283 10 Antibody Type Recombinant
Product Specification
| Host | Rabbit |
| Antigen | DLST |
| Synonyms | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; 2-oxoglutarate dehydrogenase complex component E2 (OGDC-E2); Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2K; DLTS |
| Immunogen | Synthetic Peptide |
| Location | Nucleus, Mitochondrion |
| Accession | P36957 |
| Clone Number | S-2283-10 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Bv, Pg |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
| IHC-P | 1:500 | Hu, Ms, Rt |
| ICC | 1:100 | Hu, Ms, Rt |
Background
DLST (dihydrolipoamide S-succinyltransferase) is a protein-coding gene located on chromosome 14 that encodes a mitochondrial protein belonging to the 2-oxoacid dehydrogenase family. This protein is the E2 component of the 2-oxoglutarate dehydrogenase complex, which catalyzes the conversion of 2-oxoglutarate to succinyl-CoA and CO₂, playing a crucial role in the citric acid cycle. DLST is expressed in various tissues, including the kidney and heart. Mutations in the DLST gene have been associated with diseases such as pheochromocytoma/paraganglioma syndrome.
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