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Description
PAP Recombinant Rabbit mAb (SDT-702-140)Product Specification Host Rabbit Antigen PAP Synonyms Prostatic acid phosphatase, 5' nucleotidase (5' NT), Acid phosphatase 3, Ecto 5' nucleotidase, Protein tyrosine phosphatase ACP3, Thiamine monophosphatase (TMPase), ACPP, ACP3 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Cell membrane Accession P15309 Clone Number SDT 702 140 Antibody Type Recombinant mAb Isotype IgG Application IHC P, IF Reactivity Hu Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | PAP |
| Synonyms | Prostatic acid phosphatase, 5'-nucleotidase (5'-NT), Acid phosphatase 3, Ecto-5'-nucleotidase, Protein tyrosine phosphatase ACP3, Thiamine monophosphatase (TMPase), ACPP, ACP3 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Cell membrane |
| Accession | P15309 |
| Clone Number | SDT-702-140 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P, IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:500 | |
| IF | 1:500 |
Background
Prostatic acid phosphatase (PAP) is the most abundant phosphatase in human prostate tissue/secretions. It is a clinically important protein for its relevance as a biomarker of prostate carcinoma. PAP has phosphatase activity and is an extensively studied biomarker of prostate cancer. The major action of PAP is to dephosphorylate macromolecules with the help of catalytic residues (His(12) and Asp(258)) that are located in the cleft between two domains [PMID: 20645695].
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