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Description
CEACAM-6/CD66c His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms CEACAM6, CD66c, CEAL, NCA Accession XP_014979566. 2 Amino Acid Sequence Gln35 Gly320, with C terminal 8*His
Product Specification
| Species | Cynomolgus |
| Synonyms | CEACAM6, CD66c, CEAL, NCA |
| Accession | XP_014979566.2 |
| Amino Acid Sequence | Gln35-Gly320, with C-terminal 8*His QLTIESRPFNVAEGKEVLLLAHNLPQNTLGFNWYKGERVDAKRLIVAYVIETQQTTPGPAHSGRETVYSNASLLIQNVTQNDTGSYTLQVIKGDLVNEEATGRFWVYPELPKPYITSNNSNPVEDKDAVDFTCEPDIHSTTYLWWVNDQSLPVSPRLQLSNGNRTLTLLSVKRNDAGAYECEIQNPVSANLSDPVILNVLYGPDVPTISPSNSNYRPGENLNLSCHAASNPTAQYSWFVNGTFQQSTQELFIPNITVNNSGSYMCQAYNSATGLNRTTVMMITVSGGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 55-72kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Duxbury M S. et al. (2004) Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. 23(34): 5834-5842. 2、Lewis-Wambi J S. et al. (2008) Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells. Eur J Cancer. 44(12): 1770-1779. |
Background
Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. Human CEACAM-6 is a 90 kDa, GPI-linked membrane protein that contains a 34 amino acid (aa) signal sequence, a 286 aa extracellular domain (ECD), and a 24 aa hydrophobic C-terminal propeptide. CEACAM-6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM family members are widely expressed in epithelial, endothelial, and hematopoietic cells, including neutrophils, T-cells, and NK cells. CEACAMs appear to be capable of transmitting signals that result in a variety of effects depending on the tissue, including tumor suppression, tumor promotion, angiogenesis, neutrophil activation, lymphocyte activation, regulation of the cell cycle, and regulation of adhesion. CEACAMs have now been associated with numerous intracellular signaling processes including cell adhesion, cell growth, recognition and differentiation, angiogenesis, and apoptosis.
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4.9 ★★★★★
Based on 7 reviews
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Product Reviews
★★★★★ 4
Nice casual looking sweater
Size: Small, Color: Pure Black
I purchased the black/cream inset sweater in a small. I usually wear a small. I fits loose, but NOT baggy. I like the loose fit. The sweater feels so soft. Nice looking sweater. Very happy with the sweater, but could have ordered a medium for a boxier fit.
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Reviewed in the United States on May 20, 2026
★★★★★ 5
Good quality & trendy color sweater
Size: Large, Color: Pure Apricot
This sweater is very soft, light and very suitable for keeping mild warm at the temperature of 20c or inside an air conditioning room. Particularly, the trendy color for 2026 in brown suede jacket, this sweater is real good matching item! I like it! 😍😍😍
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Reviewed in the United States on February 27, 2026
★★★★★ 5
very stylish
Size: Medium, Color: Pure Apricot
true to size. very comfortable.
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Reviewed in the United States on June 1, 2026
★★★★★ 5
Great Material
Love the sweater. So soft.
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Reviewed in the United States on May 23, 2026
★★★★★ 5
Great for layering or wearing on its own!
I’m 5’6” and ordered the small — it fits perfectly! The color is exactly as shown in the pictures, a beautiful beige that goes with everything. The fabric is incredibly soft and comfortable, making it great for layering or wearing on its own. I’m really happy with this purchase and would definitely recommend it!
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Reviewed in the United States on November 1, 2025