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Description
Sp7/Osterix Recombinant Rabbit mAb, PBS Only (SDT-3238-16)Product Specification Host Rabbit Antigen Sp7 Osterix Synonyms Transcription factor Sp7; Zinc finger protein osterix; OSX Immunogen Synthetic Peptide Location Nucleus Accession Q8TDD2 Clone Number SDT 3238 16 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IF Reactivity Hu, Ms, Rt Positive Sample Saos 2, mouse articular cartilage, mouse embryo Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | Sp7/Osterix |
| Synonyms | Transcription factor Sp7; Zinc finger protein osterix; OSX |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | Q8TDD2 |
| Clone Number | SDT-3238-16 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IF |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | Saos-2, mouse articular cartilage, mouse embryo |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu, Ms |
| IHC-P | 1:1000 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
| IF | 1:1000 | Ms, Rt |
Background
Sp7/Osterix is a ~45 kDa zinc-finger transcription factor of the Sp/KLF family that is indispensable for osteoblast lineage commitment and bone formation, acting downstream of Runx2 and cooperatively with BMP-6 to drive expression of osteogenic genes such as COL1A1, ALP, OCN, SATB2 and SOST, while its own transcription is induced by BMP-2, IGF-I and PTH and its activity is tuned by Akt- and p38 MAPK-mediated phosphorylation, ubiquitin–proteasome degradation and autoregulation via an OSX-bound tandem repeat in its promoter, and genetic or regulatory disruption of this short-lived nuclear protein underlies skeletal disorders including osteogenesis imperfecta and osteoporosis.
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4.2 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
Great Value for a Good Moisturizer (5- Stars)
Size: 3 Fl Oz (Pack of 1)
This moisturizer contains nothing fancy — and that’s the whole point. The ingredients are few but effective, with several ceramides and hyaluronic acid for deep and long-lasting hydration. Best of all, it contains no silicones or parabens. Because it’s noncomedogenic, it doesn’t cause breakouts from clogged pores. Since I have sensitive skin, all of the above are critical for my skin care routine.
It’s about as simple and as effective as a cream can get. Because of that, it doesn’t contains any sunscreen, retinol, or other anti-wrinkle components.
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Reviewed in the United States on May 18, 2026
★★★★★ 5
Excellent facial moisturizer
Size: 3 Fl Oz (Pack of 1)
Very gentle, lightweight, absorbs well without feeling greasy or heavy. Perfect to use after Fraxel laser treatment. I also like it is fragrance free and really good on sensitive skin.
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Reviewed in the United States on May 6, 2026
★★★★★ 4
Medium weight minimal ingredient moisturizer!
Size: 3 Fl Oz (Pack of 1)
As with another review, I’m looking for a replacement/dupe for Eucerin Urea Repair face moisturizer which is 5% urea
Skin concerns: dry rosacea, mid-40s, arid climate with 4 seasons, winters are cold and snowy and summers are 90°+ for most.
This is a medium-weight moisturizer that I consider not greasy at all. It is not as hydrating as I need it to be for my dry skin type with rosacea. Thickness wise I say it is similar to a standard facial sunscreen.
It does last overnight, in the morning I can still feel it in some areas. I will try increasing how much I apply in order to see if it helps with how much staying power it has. This may increase the hydration it provides and I will update my review to report back.
I had a very mild stinging sensation but my rosacea is struggling since moving to a dry climate. Once I repair my skin barrier a bit, I fully expect this will cease.
Due to this, I’m not going to get my husband to try it, he has constantly broken skin from severe eczema and stinging is something that makes him not use moisturizers. It’s a battle!
For people in more humid climates this may be a more effective moisturizer, or those with less-dry skin than me. I never have flakes so this wasn’t a parameter for me.
There is no tint. I’m not sure about white cast so I can’t rate it for skin tone. But I don’t feel there would be, this seems translucent unless you really go in with it.
For me it is reasonably effective. It’s probably a good day moisturizer and I expect it plays well with sunscreen, though I would definitely let it absorb or dry down. Which is pretty standard for daytime skin care.
There is a slight grippy feeling when applying, but this dissipates like the Eucerin Urea Repair does.
This is not, for me, a replacement or dupe for Eucerin Urea Repair. It is a great value for the price!
Overall for someone with skin like mine I rate it a very solid 4/5. I would likely purchase again for a lightweight moisturizer as a more affordable substitute for Beauty Of Joseon Dynasty Cream for day. Though this does not give me the “bounce” that does. Alas.
Updated to add: I tried increasing the amount I apply, and that eliminated any grippy feeling when applying. I now apply both day and night and this has helped repair my barrier enough it doesn’t sting when I apply this. I still have a way to go before I can return to using my sunscreen, but I do work in a building with no windows so the few minutes I am outside, it’s okay if I go without.
If I apply this to my eyes, it doesn’t sting them, which is great, my eyes are extremely sensitive and I hesitated, but it works out just fine. It isn’t thick enough to cause whiteheads to form on my lids, unlike some balm-type moisturizers (LRP!) and even unfortunately Bioderma Sensibio Eye+
I have noticed the backs of my hands are improved as I wipe off excess onto the backs of my hands and into my cuticles. I was genuinely surprised by this, it’s not like I don’t wash my hands. I wasn’t expecting it to have any effect, but the stinging scaley hands are gone, now my hands just feel normal, even after wearing wool fingerless gloves all day at work.
I will continue to use this product and will repurchase even after my financial situation improves.
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Reviewed in the United States on October 19, 2025
★★★★★ 5
My rosacea approves
Size: 3 Fl Oz (Pack of 1)
I have Rosacea, dry, sensitive, reactive skin and perimenopausal skin. My rosacea products tends to dry my already dry skin and this has been been a great moisturizer. My skin looks dewy, dullness and dryness have improved in just 2 days; I haven't reacted with sting and redness like I usually do and when I wake up I still have a dewy not greasy face even though I sleep on my sides and toss and turn all night. Definitely going to buy again since the bottle size is good, a lil goes a long way and does not make my face react like the CeraVe.
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Reviewed in the United States on April 28, 2026
★★★★★ 5
This stuff works nicely
Size: 3 Fl Oz (Pack of 1)
So I don't typically leave reviews, but I feel like this lotion has been fantastic to me. I typically don't use lotion because I hate the feel, but my face really needed it. I have dry/oily skin. My skin gets gross and flaky, yet it's pretty oily. I've always dealt with it. I decided to go ahead and buy this stuff because I couldn't take my dry skin. It helps soooo much and you barely need any. I use a dime sized amount and really focus on my problem areas. It lasts all day, not too thick and not too watery. Not greasy at all for me and soaks in very nicely. Again, it lasts all day and I don't need touch ups, even on bad skin days. I don't ever break out and it's never clogged my pores, but to be fair I've never really had skin that's broken out much before. The one thing I did notice, before using this stuff I started noticing more fine lines around my eyes/forehead. I've been using this stuff for about a year and you can barely see them anymore. I have haven't changed my diet, it's pretty atrocious honestly, so I really feel this lotion has worked wonders on its own. Also I still have a decent amount left in the bottle and I bought it almost a year ago. I'm going to try their body lotion next. Hope this helps, or at least give it a whirl!
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Reviewed in the United States on March 9, 2026