SKU: 75549573203

VDAC3 Rabbit Polyclonal Antibody

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Description

VDAC3 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen VDAC3 Synonyms Non selective voltage gated ion channel VDAC3; VDAC 3; hVDAC3Alternative nameOuter mitochondrial membrane protein porin 3 Immunogen Synthetic Peptide Location Mitochondrion Accession Q9Y277 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HEK293, Jurkat, A431, MCF7, HeLa, HepG2, MEF, NIH 3T3, mouse brain, mouse heart, PC 12, rat brain, rat

Product Specification


Host Rabbit
Antigen VDAC3
Synonyms Non-selective voltage-gated ion channel VDAC3; VDAC-3; hVDAC3Alternative nameOuter mitochondrial membrane protein porin 3
Immunogen Synthetic Peptide
Location Mitochondrion
Accession Q9Y277
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms, Rt
Positive Sample HEK293, Jurkat, A431, MCF7, HeLa, HepG2, MEF, NIH/3T3, mouse brain, mouse heart, PC-12, rat brain, rat heart
Predicted Reactivity BV, Pg, Rb, Or
Purification Immunogen Affinity
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000-1:2000 Hu, Ms, Rt
IHC-P 1:500 Hu, Ms, Rt

Background

VDAC3 (Voltage-Dependent Anion Channel 3) is a crucial isoform of the mitochondrial outer membrane porin family that distinguishes itself from its counterparts, VDAC1 and VDAC2, through unique structural features including an additional cysteine residue which facilitates the formation of intermolecular disulfide bonds and potential oligomerization. Primarily localized in the mitochondria of diverse tissues with particularly high expression in the brain, testes, and skeletal muscle, VDAC3 plays a specialized role in regulating metabolite flux, such as ATP and ADP exchange, while critically contributing to the assembly and stability of the sperm flagellar axoneme, where its dysfunction is directly linked to male infertility due to impaired sperm motility. Beyond its metabolic gating function, VDAC3 is implicated in modulating reactive oxygen species (ROS) levels and interacting with cytoskeletal elements, suggesting a broader involvement in cellular signaling pathways related to oxidative stress response and apoptosis, although its precise gating mechanisms and specific protein-protein interaction networks remain less fully characterized compared to the more ubiquitous VDAC1.

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SKU: 75549573203

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4.2 ★★★★★
Based on 25 reviews
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H. Glezos
Carnegie, US
★★★★★ 5
Best way for hot chocolate
Color: Black
works great, I use it for hot chocolate. Easy to clean. Something to consider though the Max light may be a little lower than shown depending on the milk you use.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
E
Verified Purchase
Elizabeth Cook
Alexandria, US
★★★★★ 2
Check your milk preference when buying this unit. Product Does not last
Color: White
I purchased this frother in mid Oct and less than 90 days later, it's no longer working. The wisk does not spin, and the element does not heat the milk. I am currently working with customer support on a refund / replacement, but so far not happy. I've been told it does not work with 2% organic milk and that I need to switch to whole milk, which will solve my issues. Not sure how whole milk will help with the heating element? This was not disclosed when I purchased the unit. If I had known my milk choice would impact the frother, I would have chosen another brand or product. I like the unit, it's compact, easy to clean, but it did not last.
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Reviewed in the United States on January 12, 2026
M
Verified Purchase
M. Miski
Charlottesville, US
★★★★★ 5
Easy to use, reliable machine
Color: White
Great product! I have a fully automated DeLonghi cappuccino/latte coffee machine. After 5 years of use, the machine's milk frothing function started to fail. I purchased this product to supplement/replace the milk frother on my DeLonghi automated coffee machine; it works great and produces copious milk froth with much less mess.
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Reviewed in the United States on March 18, 2026
S
Verified Purchase
Stephanie R.
Houston, US
★★★★★ 5
Best frother ever!
Color: White
This is the best frother ever! Works better than my expensive espresso machine frother. So easy and makes a large amount enough for 2 large cappuccinos.
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Reviewed in the United States on April 21, 2026
A
Verified Purchase
Amazon Customer
Grantham, US
★★★★★ 1
False advertising--it won't froth almond milk.
Color: White
Bought this because I am vegetarian and I've consumed Almond milk for the past 15 years. The profile on this product said it would froth all milks, including almond. It does not--it heats the almond milk but does not froth it. It did froth 2% cow's milk I served a visitor, but I won't use cow's milk. I missed the return date by 1 day, or it would have been returned this product for a full refund. If you want to froth plant/ nut milk, don't waste your $$$.
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Reviewed in the United States on May 9, 2026

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