SKU: 80872897726

Invivo anti-Mouse Ly6C Recombinant mAb

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Description

Invivo anti-Mouse Ly6C Recombinant mAbProduct Specification Host Rat Antigen Ly 6C Synonyms Lymphocyte antigen 6C1; Ly 6C1; Ly6c1 Location Cell membrane Accession P0CW02 Clone Number S 4036 Antibody Type Rat mAb Application FCM, in vivo macrophage depletion Reactivity Ms Purification Protein G Concentration 5 mg ml Purity >95%(Determined by SDS PAGE) Endotoxin <1EU mg Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, containing no preservative Stability &

Product Specification


Host Rat
Antigen Ly-6C
Synonyms Lymphocyte antigen 6C1; Ly-6C1; Ly6c1
Location Cell membrane
Accession P0CW02
Clone Number S-4036
Antibody Type Rat mAb
Application FCM, in vivo macrophage depletion
Reactivity Ms
Purification Protein G
Concentration 5 mg/ml
Purity >95%(Determined by SDS-PAGE)
Endotoxin <1EU/mg
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, containing no preservative
Stability & Storage

2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.

Background

Ly-6C is a glycosylphosphatidylinositol-anchored cell-surface protein belonging to the Ly-6/uPAR/α-neurotoxin superfamily, selectively expressed on murine monocyte and T-cell subsets where it serves as a dynamic lineage and activation marker—its high level on pro-inflammatory “classical” monocytes (CD11b⁺Ly-6C^hi) enables their recruitment via CCR2 to inflamed tissues, whereas Ly-6C^lo monocytes patrol vasculature and replenish resident macrophages, and transient up-regulation on CD8⁺ T cells correlates with effector differentiation; structurally it forms a three-finger α-helical bundle that can laterally associate with lipid rafts and signaling partners such as T-cell receptor or integrin complexes to modulate calcium flux, cytokine release, and adhesion, thereby critically steering innate–adaptive immune crosstalk in infections, autoimmunity, and cardiovascular disease.

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Exchange/Return Notes
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SKU: 80872897726

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4.7 ★★★★★
Based on 20 reviews
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Product Reviews
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Verified Purchase
fenglinyang
Battle Creek, US
★★★★★ 5
Great chair for everyday use
I’m really happy with this ergonomic chair. It was easy to put together and feels very sturdy once assembled. The mesh back is breathable and keeps my back cool even after sitting for hours. The seat cushion is comfortable and supportive, and the armrests are positioned well for working at a desk. I also like how smoothly the wheels roll and how easy it is to adjust the height. For the price, the quality is honestly better than I expected. I’ve been using it every day for work and it makes long sitting sessions much more comfortable. Definitely a great value and I would recommend it.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 10, 2026
A
Verified Purchase
Amazon Reviews
Port Orchard, US
★★★★★ 5
Excellent quality, comfortable for 8+ hour days
Color: Grey, Color: Grey
Since the reviews here were so very helpful to me, I decided to leave my own after using this chair a couple days. To summarize: Overall, I am thrilled with this chair and would recommend! I work remote, in a small apartment and this works well for both space saving and silence when rolling over hardwood floors all day. For more details, read on! It came packaged very nicely, so everything was well protected during shipping. There are no written instructions and to be honest, I didn't even look for them. If you've put one together before, this is pretty standard. The "leather" (not genuine, but feels like it) is thick and seems it will be sturdy for a long time. The padding is exceptional and that's the main reason I needed a new chair, as mine (a 'basic' brand one, IYKYK) only lasted one year before it felt like sitting on a hard plastic seat. The height is adjustable to go up higher than most, so for once I didn't have to raise it all the way to feel comfy. The surprisingly great thing about it is the arms that flip up, so I can push it all the way under my desk. I live in a small apartment, so every bit of space saved is a bonus! Speaking of apartments, the wheels on this are whisper quiet and I'm more than certain the neighbor below me is thrilled to not hear my clunky wheels from the other chair anymore. I was hesitant to pay too much for an office chair, but given the price and the quality, I feel it was an excellent purchase. A few items to note, if you have never put one together before: hand tighten the screws first! Don't put them on full force, until the pieces have been mostly assembled. This will help it not come out lopsided and the holes will be a little easier to line up. Watch the video, it will make the process a little easier (unlike what I did - put the arms on correctly, thought that looked wrong, then put them on backwards and lost my mind LOL). The video will also show how to recline the chair, if you like that (I do). It has a recline that's smooth as butter.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 11, 2026
J
Verified Purchase
Julia
Omaha, US
★★★★★ 5
Very comfortable and safe chair
This executive desk chair is very convenient , for its 90° flip-up armrests can be easily pushed under the desk, perfect for home office. The rubber wheels roll smoothly and quietly on my carpet. It supports up to 275 pounds so it is safe to me . The height-adjustable back with 360° swivel makes me move freely . The curved, padded backrest provides relieve back pressure , also it is very easy to set up.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 22, 2026
L
Verified Purchase
Lory Johnson
San Leandro, US
★★★★★ 4
Recommend it for all.
Color: Grey, Color: Grey
Very nice chair. One warning…it went together very easily except for the last screw!!! I finally gave up. A neighbor came over and gave up. My daughter came. Over and after much groaning and moaning got that last screw in.
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Reviewed in the United States on March 17, 2026
D
Verified Purchase
Daniel Ivan
Belleville, US
★★★★★ 5
Great for home office
Color: Grey, Color: Grey
This was a great replacement to the chair I use when I work from home, padding is firm and comfortable so I have no issue sitting on it for hours, the arm rest are foldable so is very convenient when my dogs are in co worker duty. Very easy to put together and it feels very firm and stable.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 15, 2026

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