Pay in installments of $29.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 7 - Sep 12
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
IL-1α Protein, HumanProduct Specification Species Human Synonyms IL 1A Protein, Human; IL 1F1 Protein, Human; IL1 Protein, Human; IL1 ALPHA Protein, Human; IL1F1 Protein, Human Accession Q53QF9 Amino Acid Sequence Ser113 Ala271 Expression System E. coli Molecular Weight 18kDa Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 50mM Tris,300mM NaCl,0. 2M Arginine, pH8. 0 Reconstitution
Product Specification
| Species | Human |
| Synonyms | IL-1A Protein, Human; IL-1F1 Protein, Human; IL1 Protein, Human; IL1-ALPHA Protein, Human; IL1F1 Protein, Human； |
| Accession | Q53QF9 |
| Amino Acid Sequence | Ser113-Ala271 |
| Expression System | E.coli |
| Molecular Weight | 18kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 50mM Tris,300mM NaCl,0.2M Arginine, pH8.0 |
| Reconstitution |
Reconstitute at 0.05-0.3 mg/ml according to the size in ultrapure water after rapid centrifugation
|
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1.Nicklin MJ,et al. (1994) A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes. Genomics. 19(2):382-4. 2.March CJ, et al. (1985) Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs. Nature. 315(6021):641-7. 3.Bankers-Fulbright JL, et al. (1996) Interleukin-1 signal transduction. Life Sci. 59(2):61-83. 4.Dinarello CA, et al. (1997) Induction of interleukin-1 and interleukin-1 receptor antagonist. Semin Oncol. 24 (3 Suppl 9):S9-81-S9-93. |
Background
IL-1 alpha（IL-1α） is a member of the interleukin 1 cytokine family. IL-1α control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. IL-1α is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. It is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy