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Description
Cytokeratin 7 Recombinant Rabbit mAb (SDT-R028)Product Specification Host Rabbit Antigen Cytokeratin 7 Synonyms Cytokeratin 7 (CK 7); Keratin 7 (K7); Sarcolectin; Type II keratin Kb7; KRT7 Location Cell membrane, Intracellular Accession P08729 Clone Number SDT R028 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IP, ICFCM Reactivity Hu Purification Protein A Concentration 0. 25 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | Cytokeratin 7 |
| Synonyms | Cytokeratin-7 (CK-7); Keratin-7 (K7); Sarcolectin; Type-II keratin Kb7; KRT7 |
| Location | Cell membrane, Intracellular |
| Accession | P08729 |
| Clone Number | SDT-R028 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IP, ICFCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500 | |
| IP | 1:25 | |
| IHC | 1:1000 | |
| ICC | 1:50 | |
| ICFCM | 1:500 |
Background
Cytokeratin 7 is the intermediate silk protein mainly expressed in epithelial cells. The heterodine of keratin consists of a polymerization filament by an acid -keratin (or type I keratin, keratin 9 to 23) and alkaline keratin (or type II keratin, keratin 1 to 8). Expression similar to but more limited than keratins 8 and 18 in simple, pseudostratified and ductal epithelium, mesothelium and urothelium. It's generally expressed (with some variation) in adenocarcinoma of lung, breast, thyroid, endometrium, cervix, ovary, salivary gland, upper GI tract, urothelial carcinoma, papillary renal cell carcinoma and Paget disease. It's generally negative (with some variation) in colorectal carcinoma, Merkel cell carcinoma, hepatocellular carcinoma, prostatic adenocarcinoma, adrenocortical tumors and squamous cell carcinoma.
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Exchange/Return Notes
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