SKU: 15342576768

Alexa Fluor® 700 Mouse Anti-Human CD56 Antibody (S-3499)

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Description

Alexa Fluor® 700 Mouse Anti-Human CD56 Antibody (S-3499)Product Specification Host Mouse Antigen CD56 Synonyms Neural cell adhesion molecule 1; N CAM 1; NCAM 1; CD56; NCAM; NCAM1 Location Secreted, Cell membrane Accession P13591 Clone Number S 3499 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &

Product Specification


Host Mouse
Antigen CD56
Synonyms Neural cell adhesion molecule 1; N-CAM-1; NCAM-1; CD56; NCAM; NCAM1
Location Secreted, Cell membrane
Accession P13591
Clone Number S-3499
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 700
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

Neural cell adhesion molecule 1 (NCAM-1), also known as CD56, is a cell adhesion protein belonging to the immunoglobulin superfamily. It is expressed on various cell types including neurons, muscle cells, and immune cells like natural killer (NK) cells. NCAM-1/CD56 plays crucial roles in cell-to-cell and cell-matrix interactions during development and differentiation, regulating processes such as neurogenesis, neurite outgrowth, axonal guidance, and cell migration in the nervous system. In the immune system, it is involved in the expansion of T lymphocytes, B lymphocytes, and NK cells. NCAM-1/CD56 also triggers signaling cascades involving FYN-focal adhesion kinase (FAK), mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinase (PI3K). Additionally, it serves as a biomarker for certain diseases, such as malignant tumors in the nervous system and neuroendocrine carcinoma.

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SKU: 15342576768

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4.6 ★★★★★
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Stephen M.
Fort Morgan, US
★★★★★ 5
A Clear, Readable, and Necessary Contribution
Format: Paperback
This is a clear, readable, and necessary book. The Trinity is the central mystery of the Christian faith, but it can be difficult to articulate in a simple and coherent way. As one who regularly teaches the topic in the Catholic high school setting, I appreciated the very accessible approach that the author takes. Anyone who struggles with the basic meaning of the doctrine would benefit from this text, as would those who are tasked with explaining it to others. From the very first page of the book, the author presents the doctrine of the Trinity through three basic statements: 1. There is only one God. 2. The Father, the Son, and the Holy Spirit is each God. 3. The Father, the Son, and the Holy Spirit are not the same. Besides a very good opening chapter on the ability to speak about God at all, the entire book is basically an unpacking of why the Church came to believe in these three statements and the problems (aka heresies) that arise when any one of the three is denied. Over the course of the book, the reader will become familiar with many of the key biblical texts underlying the doctrine of the Trinity and the early theologians who defended it. While this is not primarily a work of doctrinal history, the arguments are almost entirely based on the thought of these fourth and fifth century theologians. Two points are worth noting, though neither was a "deal breaker" for me: First, be ready for lots of references to popular culture. I was surprised to see mentions of everything from Wayne's World and Borat to the song Achy Breaky Heart and the Three Amigos. These are no doubt great examples from the author's experience, as university teacher, in connecting the subject matter to his student audience. But in almost every instance I found myself drawn away from the topic at hand and in some cases I was left pondering the usefulness of the gratuitous reference itself. Luckily, I got almost every single one--until a late reference to the British TV series Father Ted forced me to look it up on Google. Second, I'm not sure if this book is still in such an early printing that it hasn't been physically typeset yet, but my edition looked as though an inkjet printer produced it. In an age of Retina display screens, it was a bit odd being disappointed in the quality of actual printed text. Overall, I highly recommend the book. I've just ordered the author's previous book from Paulist Press and look forward to his future works.
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Reviewed in the United States on May 3, 2015
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ILOVEMYKINDLE
Fort Morgan, US
★★★★★ 4
This book is good if you wish to know the heresies of the ...
Format: Kindle
This book is good if you wish to know the heresies of the Trinity. It does not cover the inner working relationships of the Trinity.
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Reviewed in the United States on March 18, 2016
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bevo in the nw
Pawtucket, US
★★★★★ 5
It doesn't have to be a mystery
Format: Paperback
The answer almost every Catholic including the clergy give regarding the Trinity is "its a mystery." Its not if you read Bullivant it is now a discussion and conversation about the Christian understanding of God. Now the person in the pew can help explain "the mystery" to the clergy who haven't read The Trinity. The author introduces the Trinity as "supreme simplicity" and then guides discussion through an adult presentation of a fundamental belief among Christians. The style is very conversational with wonderful and one could say fun examples. The author makes excellent use of scripture and the writings of the early Christian church before all the disputes and splits started. He does it all in about a 100 pages. Perfect for the curious, those wanting a real answer about the Trinity and for small study groups. Finally it is done with an ecumenical approach that allows Christians to dialogue together and with those with different or no faith tradition.
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Reviewed in the United States on April 14, 2015
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Ice
Charlottesville, US
★★★★★ 5
Excellent Introduction
Format: Kindle
Bullivant, as simply and straightforwardly as possible, provides an excellent Introduction to this most central of Christian doctrine in an educated yet graspable format. Highly recommended.
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Reviewed in the United States on October 16, 2023
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Robert Badger
Battle Creek, US
★★★★★ 5
This book is a good introduction to the theology of the Trinity
Format: Paperback
As a Catholic priest, I am on the lookout for books which may help those who want to delve more deeply into theology. This book is a good introduction to the theology of the Trinity. Professor Bullivant shows why it is biblical. He also explains some of the more difficult terminology very well. Also, his opening chapter provides a memorable explanation of the via negativa in theology. I highly recommend this text.
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Reviewed in the United States on February 22, 2017

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