SKU: 22043600480

FITC Mouse Anti-Human CD14 Antibody (S-3449)

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Description

FITC Mouse Anti-Human CD14 Antibody (S-3449)Product Specification Host Mouse Antigen CD14 Synonyms Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell specific leucine rich glycoprotein Location Cell membrane Accession P08571 Clone Number S 3449 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300

Product Specification


Host Mouse
Antigen CD14
Synonyms Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein
Location Cell membrane
Accession P08571
Clone Number S-3449
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein A
Concentration 0.2 mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD14 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein primarily expressed on monocytes, macrophages, and some granulocytes. It functions as a pattern recognition receptor (PRR) and plays a crucial role in the innate immune response by recognizing bacterial lipopolysaccharides (LPS), pathogen-associated molecular patterns (PAMPs), and damage-associated molecular patterns (DAMPs). CD14 exists in two forms: membrane-bound CD14 (mCD14) and soluble CD14 (sCD14), which can be secreted by activated cells. It acts as a co-receptor for Toll-like receptor 4 (TLR4) and enhances the immune response to LPS by facilitating its delivery to the TLR4-MD2 complex. Additionally, CD14 is involved in TLR4-independent signaling pathways and contributes to tissue homeostasis by promoting the clearance of apoptotic cells.

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SKU: 22043600480

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4.9 ★★★★★
Based on 26 reviews
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Product Reviews
S
Verified Purchase
Stacy H
Los Angeles, US
★★★★★ 5
Must-Have for Active Dogs!
Style: Sport, Size: Large
The Chuckit Sport 26L Dog Ball Launcher has been a game-changer for my large dog! My 80-pound Labrador loves to play fetch, and this launcher makes it so much easier and more enjoyable for both of us. The 26” length gives me the leverage to throw the ball much farther than I could by hand, which really helps burn off my dog’s energy. The included large ball (3”) is the perfect size for big dogs, and I appreciate that it’s made from durable rubber, so it withstands a lot of chewing and rough play. What I really love is that the launcher is so lightweight and easy to use. I can play fetch with my dog for extended periods without my arm getting tired. The ergonomic handle also provides a comfortable grip, which is a nice touch. If you have a large, active dog, the Chuckit Sport 26L is a must-have. It’s well-made, durable, and makes fetch more fun for both you and your dog. Highly recommend!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 3, 2024
D
Verified Purchase
DD
Fort Morgan, US
★★★★★ 5
ChuckIt is AMAZING!
Style: Sport, Size: Large
I can't throw a ball to save my soul. Just got this today and lobbed a ball to the far end of my 1- acre yard. The dog loves it, and I love it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 8, 2026
S
Verified Purchase
Sean
Boise, US
★★★★★ 4
I recommend using the KONG Extreme Dog Toy
Style: Sport, Size: Large
Helpful for throwing as much as my dog wants to fetch. I actually had to get a cortisone injection in my shoulder a few months after getting my dog - never had a dog with this much energy before! The Chuckit really helps. Downside: The ball that comes with it is larger than a tennis ball, so may be too much for smaller doge. I can't imagine my sister-in-law's french bulldog carrying it! Also, in our house it gets destroyed within minutes, as my dog is a strong chewer. For this situation, I recommend using the KONG Extreme Dog Toy, Black, size Large. This is shaped sort of like a snowman, which means it bounces unpredictably at times. My dog eventually chews the "head" off of this toy, but the remaining 2/3 still fits in the Chuckit (and is actually easier to throw with the "head" missing!). One caveat: the KONG is significantly heavier than the ball included with the Chuckit, so be aware of that... Also, we ordered our first Chickit in October 2015, then needed to replace it in May of 2017, as it broke. I think the plastic became brittle over that time, as we left it out in the sun & rain in Florida. Since it is cheap to replace, that's not a big deal. (We ordered three Kong toys over that same period of time!) To summarize, it's a very helpful tool to get the ball further, faster, with less strain, than without it. Knowing there are alternatives to the included ball for heavy chewers makes it worthwhile.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 19, 2017
D
Verified Purchase
DesertRoads
Cuba, US
★★★★★ 5
Great Ball Launcher!
Style: Sport, Size: Large
Our dogs love this ball launcher! I can throw the ball long distances without any arm strain. The balls wear out, and as described by others, tennis balls don’t fit. Buy extra balls if this is of concern. We bought a few of the “Chuck It” rubber 3” balls and they have worked well for our dogs. It’s a great value and fun for the dogs.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 28, 2025
C
Verified Purchase
Cheri Who
Charlottesville, US
★★★★★ 5
Chuckit!! Just Chuck it!!
Style: Sport, Size: Large
Chuck it further than your skinny little arms can chuck it. Doggo loved this, I loved this and when we were done Doggo promptly hid it under the porch so I couldn’t take it from him. It’s not a squeaky toy, it’s for fetch. You wing it out toward the yard and it flies, bounces if it’s lucky then is attacked in an adoring manner. We like it!!
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Reviewed in the United States on May 31, 2026

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