SKU: 5718482254

FMC63 Recombinant Rabbit mAb (APC Conjugate) (S-2163-77)

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Description

FMC63 Recombinant Rabbit mAb (APC Conjugate) (S-2163-77)Product Specification Immunogen Recombinant Protein Clone Number S 2163 77 Antibody Type Recombinant mAb Isotype IgG Application FCM Purification Protein A Concentration 0. 2 mg ml Conjugation APC Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied Dilution application dilution species FCM 5l per million cells in 100l volume Species independent

Product Specification


Immunogen Recombinant Protein
Clone Number S-2163-77
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Purification Protein A
Concentration 0.2 mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Species independent

Background

FMC63 scFv (single-chain variable fragment) is a recombinant protein derived from the variable regions (VH and VL) of the anti-CD19 monoclonal antibody FMC63, linked by a flexible peptide spacer (e.g., (Gly₄Ser)₃). It specifically binds to the B-cell surface antigen CD19 with high affinity (KD ~1-10 nM) and is a key targeting component in FDA-approved CAR-T therapies, such as Kymriah®. The humanized FMC63 scFv retains potent antigen recognition while minimizing immunogenicity, making it highly effective in treating B-cell malignancies, including acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL). Ongoing research focuses on optimizing its affinity, stability, and functionality to enhance the safety and efficacy of CAR-T cell therapies.

Shipping Notes
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Exchange/Return Notes
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SKU: 5718482254

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4.0 ★★★★★
Based on 15 reviews
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Product Reviews
S
Verified Purchase
Stacy H
Draper, US
★★★★★ 5
Must-Have for Active Dogs!
Style: Sport, Size: Large
The Chuckit Sport 26L Dog Ball Launcher has been a game-changer for my large dog! My 80-pound Labrador loves to play fetch, and this launcher makes it so much easier and more enjoyable for both of us. The 26” length gives me the leverage to throw the ball much farther than I could by hand, which really helps burn off my dog’s energy. The included large ball (3”) is the perfect size for big dogs, and I appreciate that it’s made from durable rubber, so it withstands a lot of chewing and rough play. What I really love is that the launcher is so lightweight and easy to use. I can play fetch with my dog for extended periods without my arm getting tired. The ergonomic handle also provides a comfortable grip, which is a nice touch. If you have a large, active dog, the Chuckit Sport 26L is a must-have. It’s well-made, durable, and makes fetch more fun for both you and your dog. Highly recommend!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 3, 2024
D
Verified Purchase
DD
Boise, US
★★★★★ 5
ChuckIt is AMAZING!
Style: Sport, Size: Large
I can't throw a ball to save my soul. Just got this today and lobbed a ball to the far end of my 1- acre yard. The dog loves it, and I love it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 8, 2026
S
Verified Purchase
Sean
Bozeman, US
★★★★★ 4
I recommend using the KONG Extreme Dog Toy
Style: Sport, Size: Large
Helpful for throwing as much as my dog wants to fetch. I actually had to get a cortisone injection in my shoulder a few months after getting my dog - never had a dog with this much energy before! The Chuckit really helps. Downside: The ball that comes with it is larger than a tennis ball, so may be too much for smaller doge. I can't imagine my sister-in-law's french bulldog carrying it! Also, in our house it gets destroyed within minutes, as my dog is a strong chewer. For this situation, I recommend using the KONG Extreme Dog Toy, Black, size Large. This is shaped sort of like a snowman, which means it bounces unpredictably at times. My dog eventually chews the "head" off of this toy, but the remaining 2/3 still fits in the Chuckit (and is actually easier to throw with the "head" missing!). One caveat: the KONG is significantly heavier than the ball included with the Chuckit, so be aware of that... Also, we ordered our first Chickit in October 2015, then needed to replace it in May of 2017, as it broke. I think the plastic became brittle over that time, as we left it out in the sun & rain in Florida. Since it is cheap to replace, that's not a big deal. (We ordered three Kong toys over that same period of time!) To summarize, it's a very helpful tool to get the ball further, faster, with less strain, than without it. Knowing there are alternatives to the included ball for heavy chewers makes it worthwhile.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 19, 2017
D
Verified Purchase
DesertRoads
Battle Creek, US
★★★★★ 5
Great Ball Launcher!
Style: Sport, Size: Large
Our dogs love this ball launcher! I can throw the ball long distances without any arm strain. The balls wear out, and as described by others, tennis balls don’t fit. Buy extra balls if this is of concern. We bought a few of the “Chuck It” rubber 3” balls and they have worked well for our dogs. It’s a great value and fun for the dogs.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 28, 2025
C
Verified Purchase
Cheri Who
Massapequa, US
★★★★★ 5
Chuckit!! Just Chuck it!!
Style: Sport, Size: Large
Chuck it further than your skinny little arms can chuck it. Doggo loved this, I loved this and when we were done Doggo promptly hid it under the porch so I couldn’t take it from him. It’s not a squeaky toy, it’s for fetch. You wing it out toward the yard and it flies, bounces if it’s lucky then is attacked in an adoring manner. We like it!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 31, 2026

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