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Description
LYPD8 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms LYPD8, LY6, PLAUR domain containing 8 Accession Q6UX82 Amino Acid Sequence Leu20 Asn215, with C terminal Human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | LYPD8, LY6, PLAUR domain containing 8 |
| Accession | Q6UX82 |
| Amino Acid Sequence | Leu20-Asn215, with C-terminal Human IgG1 Fc LSCVQCNSWEKSCVNSIASECPSHANTSCISSSASSSLETPVRLYQNMFCSAENCSEETHITAFTVHVSAEEHFHFVSQCCQGKECSNTSDALDPPLKNVSSNAECPACYESNGTSCHGKPWKCYEEEQCVFLVAELKNDIESKSLVLKGCSNVSNATCQFLSGENKTLGGVIFRKFECANVNSLTPTSAPTTSHNIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 60-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Okumura R. et al. (2020) Lypd8 inhibits attachment of pathogenic bacteria to colonic epithelia. Mucosal Immunol. 13: 75-85. |
Background
Lypd8 is a highly N-glycosylated glycosylphosphatidylinositol-anchored protein that is highly expressed on colonic IECs and constitutively shed into the intestinal lumen. Lypd8 inhibits the invasion of colonic epithelia by flagellated commensal bacteria such as Proteus mirabilis and E. coli belonging to Enterobacteriaceae family by suppressing their motility via flagella binding. However, it remains unclear whether Lypd8 has a protective function against pathogenic bacteria, including pathogenic E. coli, Salmonella, Shigella, and Citrobacter, many of which belong to the family Enterobacteriaceae.
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4.1 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 5
Favorite Winter Bedding!
Color: Red Buffalo Plaid, Size: King
Cozy, warm, and so so soft! Washes up beautifully! A great bed set for the cost. Thank you!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 27, 2026
★★★★★ 5
Love it!
Color: Red Buffalo Plaid, Size: Full/Queen
Instantly became my favorite comforter for winter months. Colors are vibrant and beautiful; soft and warm; appears to be durable. I would get another of it came in others colors. Paired with the Amazon Basics red buffalo plaid sheet set. Matches my pajamas and my dogs’ bandannas perfectly!
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Reviewed in the United States on December 1, 2025
★★★★★ 5
Good product
Size: Queen, Color: Light Grey
Just perfect, fit exactly as intended
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Reviewed in the United States on June 6, 2026
★★★★★ 5
Lightweight, Easy to Install, and Holds Up Well
Size: Full, Color: Black
This bed skirt has been a great purchase. It’s very lightweight, which actually made it super easy to put on the bed without a struggle. Once in place, it looks nice and does exactly what it’s supposed to do.
It’s also held up well to my almost-teenager being a little reckless at times, no tearing or issues so far. For the price, it’s definitely a good value.
Overall, simple, functional, and worth it if you need a clean finished look for your bed.
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Reviewed in the United States on February 19, 2026
★★★★★ 4
Great for the price
Size: Full, Color: Bright White
Great for the price. The fabric is thin and not made well but for the price it’ll do. Must iron it so that it lays correctly but I figured I’d have to.
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Reviewed in the United States on April 9, 2026
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