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Description
Olfm4 Recombinant Rabbit mAb (S-2748-67)Product Specification Host Rabbit Antigen Olfm4 Synonyms Olfactomedin 4; OLM4 Immunogen Synthetic Peptide Location Secreted, Mitochondrion Accession Q3UZZ4 Clone Number S 2748 67 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Ms, Rt Positive Sample mouse spleen, rat spleen Purification Protein A Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03%
Product Specification
| Host | Rabbit |
| Antigen | Olfm4 |
| Synonyms | Olfactomedin-4; OLM4 |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Mitochondrion |
| Accession | Q3UZZ4 |
| Clone Number | S-2748-67 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Ms, Rt |
| Positive Sample | mouse spleen, rat spleen |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms, Rt |
| IHC-P | 1:2000 | Ms, Rt |
Background
Olfm4 (olfactomedin-4) is a secreted glycoprotein highly expressed in intestinal stem cells, bone marrow neutrophils and prostate epithelium that acts as a context-dependent modulator of cell adhesion, innate immunity and apoptosis by binding cadherins and lectins, potentiating Wnt/Notch signaling to promote epithelial regeneration, and interacting with GRIM-19 to suppress mitochondrial apoptosis, while its frequent up-regulation in gastric, colorectal and other cancers fuels tumor growth, metastasis and chemoresistance and makes it a valuable serum biomarker.
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Exchange/Return Notes
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