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Description
NG2/CSPG4 His Tag Protein, HumanProduct Specification Species Human Synonyms neuron glial antigen 2, NG2, high molecular weight melanoma associated antigen, HMW MAA) Accession Q6UVK1 Amino Acid Sequence Ser1583 Ser2224, with C terminal 10*His
Product Specification
| Species | Human |
| Synonyms | neuron-glial antigen 2, NG2, high molecular weight-melanoma associated antigen, HMW-MAA) |
| Accession | Q6UVK1 |
| Amino Acid Sequence | Ser1583-Ser2224, with C-terminal 10*His SLKGSQTLTVCPGSVQPLSSQTLRASSSAGTDPQLLLYRVVRGPQLGRLFHAQQDSTGEALVNFTQAEVYAGNILYEHEMPPEPFWEAHDTLELQLSSPPARDVAATLAVAVSFEAACPQRPSHLWKNKGLWVPEGQRARITVAALDASNLLASVPSPQRSEHDVLFQVTQFPSRGQLLVSEEPLHAGQPHFLQSQLAAGQLVYAHGGGGTQQDGFHFRAHLQGPAGASVAGPQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRFTQADVDSGRLAFVANGSSVAGIFQLSMSDGASPPLPMSLAVDILPSAIEVQLRAPLEVPQALGRSSLSQQQLRVVSDREEPEAAYRLIQGPQYGHLLVGGRPTSAFSQFQIDQGEVVFAFTNFSSSHDHFRVLALARGVNASAVVNVTVRALLHVWAGGPWPQGATLRLDPTVLDAGELANRTGSVPRFRLLEGPRHGRVVRVPRARTEPGGSQLVEQFTQQDLEDGRLGLEVGRPEGRAPGPAGDSLTLELWAQGVPPAVASLDFATEPYNAARPYSVALLSVPEAARTEAGKPESSTPTGEPGPMASSPEPAVAKGGFLSFLEANMFSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 90-110 kDa(Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
CSPG4 (also known as neuron-glial antigen 2, NG2, and high molecular weight-melanoma associated antigen, HMW-MAA) is key component of cell migration and proliferation. CSPG4 has been associated with disease severity in other tumors. Expression of CSPG4 could be a useful prognostic biomarker in chordoma. As CSPG4 is expressed on the cell-surface, it is also an attractive candidate for targeting by a CSPG4-specific antibody.
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