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Description
Human IgG4 Fc , His tagProduct Specification Species Human Synonyms Ig gamma 4 chain C region, IGHG4 Accession P01861 Amino Acid Sequence Protein sequence(P01861, Glu99 Gly326, with C 10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH Expression System HEK293 Molecular Weight
Product Specification
| Species | Human |
| Synonyms | Ig gamma-4 chain C region, IGHG4 |
| Accession | P01861 |
| Amino Acid Sequence | Protein sequence(P01861, Glu99-Gly326, with C-10*His) ESKYGPPCPSCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.3kDa Actual:33kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | with C-10*His |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
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Exchange/Return Notes
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4.4 ★★★★★
Based on 30 reviews
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Product Reviews
★★★★★ 5
perfect for tiny breeds!
Color: Blue
this toy is the perfect size for my mini dauchshund mix puppy. I looked in several pet stores for a tug of war rope for something for my little two pound pup that wasn't my socks for him to tug on. so many rope toys are aimed for large breeds, and were larger than my dog himself
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Reviewed in the United States on June 10, 2026
★★★★★ 5
MINPIN LOVES HIS NEW TOY!!!
Color: Blue
My minpin LOVES this toy! Very small just the perfect size for tiny dogs!!!! Durable!!!!
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Reviewed in the United States on June 8, 2026
★★★★★ 4
Cute size but didn’t last
Color: Blue
I love Kong toys. I bought for my two puppies. One is already broke. But still works like a good tug of war rope with a bonus chew bone.
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Reviewed in the United States on May 9, 2026
★★★★★ 3
End of rope your dog or puppy can get the sting in it's mouth
Color: Blue
My puppy loves this toy ,but she can pull the string fiber off the rope so you have to watch that they don't eat the string. Wish the rope was made different with a hard knot at the ends. But my puppy loves the toy .I will just fix the end myself.
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Reviewed in the United States on December 5, 2025
★★★★★ 1
Flimsy
Color: Pink
Rope broke with first pull during playtime. Also is very small.
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Reviewed in the United States on May 28, 2026