SKU: 78314618229

SEZ6 Recombinant Rabbit mAb,PBS Only(SDT-2097-7)

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Description

SEZ6 Recombinant Rabbit mAb,PBS Only(SDT-2097-7)Product Specification Host Rabbit Antigen SEZ6 Synonyms Seizure protein 6 homolog; SEZ 6; hSEZ 6 Immunogen Recombinant Protein Location Cell membrane Accession Q53EL9 Clone Number SDT 2097 7 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample H69 Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt

Product Specification


Host Rabbit
Antigen SEZ6
Synonyms Seizure protein 6 homolog; SEZ-6; hSEZ-6
Immunogen Recombinant Protein
Location Cell membrane
Accession Q53EL9
Clone Number SDT-2097-7
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Positive Sample H69
Purification Protein A
Concentration 1 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000-1:5000 Hu
IHC-P 1:250 Hu

Background

SEZ6 (Seizure-related gene 6) is a type I transmembrane glycoprotein (~110 kDa) composed of five short consensus repeat (SCR) domains, three CUB domains, a single transmembrane segment and a short cytoplasmic tail that is predominantly expressed in the central nervous system, where it acts as a critical trafficking chaperone for kainate receptor subunits GluK2/3, ensuring their proper N-glycosylation (including the HNK-1 epitope), post-ER export and surface localization to regulate synaptic connectivity, long-term potentiation and dendritic arbor balance, and is sequentially cleaved by BACE1 and γ-secretase to release a soluble ectodomain whose CSF level serves as a direct pharmacodynamic read-out of BACE1 inhibition, while in neuroendocrine neoplasms its selective over-expression is exploited as an ADC target for therapies against small-cell lung cancer and related tumors.

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SKU: 78314618229

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4.0 ★★★★★
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Kerri Campbell
Charlottesville, US
★★★★★ 5
A Great Graduation Gift
Format: Hardcover
This was one of my favorite books when I was a child. I've been purchasing this as a graduation gift for years. I gave it to both my daughters when they graduated high school and was happy to read that very copy we gifted our daughter to my granddaughter. The book has also helped me in some difficult times of my own life. Dr. Seuss is timeless and this makes a great gift.
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Reviewed in the United States on May 12, 2026
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Natalie H.
Massapequa, US
★★★★★ 5
The Perfect Gift for a New Beginning
Format: Hardcover
Oh, the Places You'll Go! by Dr. Seuss is a timeless and encouraging read filled with humor, wisdom, and inspiration about life’s journey and all of its ups and downs. This is such a meaningful gift for a high school senior, graduate, or anyone stepping into a new chapter of life.
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Reviewed in the United States on May 7, 2026
M
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Maria
Pawtucket, US
★★★★★ 5
I recommend using this book. Read review.
Format: Hardcover
I recommend this book. Not only because it's a Dr. Sue's book, but because at the end of the school year. I ask my son's teacher to sign it. It's a sweet memory to have and it will be a sweet memory to look at once they graduate Elementary. It's a must. The price is great. Quality... Everything about it is great. Most of all.... Reading the their teacher's have to say about them. Is so sweet!
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Reviewed in the United States on May 23, 2026
M
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Mommy Sarah
Lake Worth, US
★★★★★ 5
Dr. Suess. Enough Said.
Format: Hardcover, Format: Hardcover
Welcome to the whimsical world of Dr. Seuss, where "Oh, the Places You'll Go!" isn't just a book—it's a roadmap to life's most thrilling escapades! If life were a rollercoaster, this book would be the front-row seat to the wildest ride of all. From the moment you crack open its vibrant pages, you're whisked away on an exhilarating journey filled with colorful landscapes, quirky characters, and nuggets of wisdom disguised in Seussian rhymes. It's a literary wonderland where imagination reigns supreme, and the words dance off the pages, pulling you into an adventure unlike any other. Dr. Seuss, the maestro of whimsy and wonder, takes you on a whirlwind exploration of life's ups and downs, encouraging you to embrace every twist, turn, and unexpected detour with unbridled enthusiasm. Whether you're just starting out on life's path or navigating its winding roads, this book serves as a beacon of hope, inspiration, and boundless possibilities. Now, let's talk about the humor woven into every verse—oh, it's a riot! Dr. Seuss's playful language and zany illustrations transform life's perplexities into delightful puzzles to solve. You'll find yourself chuckling at the absurdity of the situations and nodding knowingly at the profound truths hidden within the jest. And oh, the illustrations! They're a visual feast for the eyes, bursting with vibrant hues and fantastical landscapes that transport you to worlds beyond your wildest dreams. The whimsical characters and their expressions evoke emotions that range from sheer joy to contemplative reflection, leaving an indelible mark on your heart. But wait, there's more! This book isn't just for kids—it's a timeless gem that resonates with readers of all ages. Whether you're 8 or 80, the wisdom embedded in its verses speaks volumes about the human spirit's resilience, determination, and unwavering courage to conquer life's myriad challenges. In essence, "Oh, the Places You'll Go!" isn't merely a book; it's a celebration of life's rollercoaster, a symphony of laughter, and a profound reminder that the journey itself is the greatest adventure of all. So, buckle up, embrace the whimsy, and get ready to soar to unimaginable heights—you're in for an exhilarating ride! *Disclaimer: May induce spontaneous outbreaks of giggles and an insatiable thirst for adventure!*
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Reviewed in the United States on November 15, 2023
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Eve Allen
Bozeman, US
★★★★★ 5
Oh, the places you'll go! Book Review
Format: Hardcover
Perfect hardcover book for such an affordable price!
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Reviewed in the United States on May 25, 2026

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