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Description
HNF4α Recombinant Rabbit mAb (SDT-373-64)Product Specification Host Rabbit Antigen HNF4 Synonyms Hepatocyte nuclear factor 4, NR2A1, HNF 4 alpha, HNF 4, TCF 14 Immunogen Recombinant Protein Location Nucleus Accession P49698 Clone Number SDT 373 64 Antibody Type Recombinant mAb Application WB, IHC P, ICC, IP, ICFCM Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability &
Product Specification
| Host | Rabbit |
| Antigen | HNF4α |
| Synonyms | Hepatocyte nuclear factor 4, NR2A1, HNF-4-alpha, HNF-4, TCF-14 |
| Immunogen | Recombinant Protein |
| Location | Nucleus |
| Accession | P49698 |
| Clone Number | SDT-373-64 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, IP, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500 | |
| ICC | 1:500 | |
| IP | 1:50 | |
| ICFCM | 1:500 |
Background
HNF4α is a transcription factor that plays an important role in liver morphogenesis and maintenance of proper hepatocyte function in a mature liver. Most liver diseases have been associated with altered HNF4α expression, isoform ratios, and localization. Therefore, many studies have indicated that HNF4α may potentially be a target gene for the regression of fibrosis and cirrhosis [PMID: 35114889].
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