Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 3 - Sep 8
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
APC6 Recombinant Rabbit mAb (S-2550-48)Product Specification Host Rabbit Antigen APC6 Synonyms Cell division cycle protein 16 homolog; Anaphase promoting complex subunit 6 (APC6); Cyclosome subunit 6; Anapc6; Cdc16 Immunogen Recombinant Protein Location Cytoplasm, Nucleus Accession Q8R349 Clone Number S 2550 48 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Positive Sample NIH 3T3, mouse liver, C6, rat brain Purification Protein A Concentration
Product Specification
| Host | Rabbit |
| Antigen | APC6 |
| Synonyms | Cell division cycle protein 16 homolog; Anaphase-promoting complex subunit 6 (APC6); Cyclosome subunit 6; Anapc6; Cdc16 |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm, Nucleus |
| Accession | Q8R349 |
| Clone Number | S-2550-48 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | NIH/3T3, mouse liver, C6, rat brain |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1: 2000 | Ms, Rt |
| IHC-P | 1:100-1: 1000 | Hu, Ms, Rt |
Background
APC6 (also known as CDC16) is a core scaffolding subunit of the anaphase-promoting complex/cyclosome (APC/C), a multi-subunit E3 ubiquitin ligase that governs cell cycle progression by targeting key regulatory proteins such as cyclins and securin for proteasomal degradation; APC6 contains multiple tetratricopeptide repeats (TPRs) that mediate protein-protein interactions essential for APC/C integrity and is stabilized by the small subunit CDC26, ensuring proper ubiquitin transfer and timely transition from metaphase to anaphase, thereby safeguarding genomic stability.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy